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21 results

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Page 1
Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction.
Llona-Minguez S, Throup A, Steiner E, Lightowler M, Van der Haegen S, Homan E, Eriksson L, Stenmark P, Jenmalm-Jensen A, Helleday T. Llona-Minguez S, et al. Org Biomol Chem. 2017 Sep 26;15(37):7758-7764. doi: 10.1039/c7ob02069d. Org Biomol Chem. 2017. PMID: 28891572
Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
Llona-Minguez S, Höglund A, Ghassemian A, Desroses M, Calderón-Montaño JM, Burgos Morón E, Valerie NCK, Wiita E, Almlöf I, Koolmeister T, Mateus A, Cazares-Körner C, Sanjiv K, Homan E, Loseva O, Baranczewski P, Darabi M, Mehdizadeh A, Fayezi S, Jemth AS, Warpman Berglund U, Sigmundsson K, Lundbäck T, Jenmalm Jensen A, Artursson P, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2017 May 25;60(10):4279-4292. doi: 10.1021/acs.jmedchem.7b00182. Epub 2017 May 16. J Med Chem. 2017. PMID: 28508636
Chemical strategies for development of ATR inhibitors.
Llona-Minguez S, Höglund A, Jacques SA, Koolmeister T, Helleday T. Llona-Minguez S, et al. Expert Rev Mol Med. 2014 May 9;16:e10. doi: 10.1017/erm.2014.10. Expert Rev Mol Med. 2014. PMID: 24810715 Review.
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.
Llona-Minguez S, Höglund A, Jacques SA, Johansson L, Calderón-Montaño JM, Claesson M, Loseva O, Valerie NCK, Lundbäck T, Piedrafita J, Maga G, Crespan E, Meijer L, Morón EB, Baranczewski P, Hagbjörk AL, Svensson R, Wiita E, Almlöf I, Visnes T, Jeppsson F, Sigmundsson K, Jensen AJ, Artursson P, Jemth AS, Stenmark P, Berglund UW, Scobie M, Helleday T. Llona-Minguez S, et al. J Med Chem. 2016 Feb 11;59(3):1140-1148. doi: 10.1021/acs.jmedchem.5b01741. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26771665 Free PMC article.
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, Wallner O, Isaksson R, Carter M, Rudd SG, Loseva O, Jemth AS, Almlöf I, Font-Mateu J, Llona-Minguez S, Baranczewski P, Jeppsson F, Homan E, Almqvist H, Axelsson H, Regmi S, Gustavsson AL, Lundbäck T, Scobie M, Strömberg K, Stenmark P, Beato M, Helleday T. Page BDG, et al. Among authors: llona minguez s. Nat Commun. 2018 Jan 17;9(1):250. doi: 10.1038/s41467-017-02293-7. Nat Commun. 2018. PMID: 29343827 Free PMC article.
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Page BDG, Valerie NCK, Wright RHG, Wallner O, Isaksson R, Carter M, Rudd SG, Loseva O, Jemth AS, Almlöf I, Font-Mateu J, Llona-Minguez S, Baranczewski P, Jeppsson F, Homan E, Almqvist H, Axelsson H, Regmi S, Gustavsson AL, Lundbäck T, Scobie M, Strömberg K, Stenmark P, Beato M, Helleday T. Page BDG, et al. Among authors: llona minguez s. Nat Commun. 2019 Nov 1;10(1):5050. doi: 10.1038/s41467-019-12806-1. Nat Commun. 2019. PMID: 31676755 Free PMC article.
21 results