Okabe H - Search Results

1

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts.

Tsukihara H, Nakagawa F, Sakamoto K, Ishida K, Tanaka N, Okabe H, Uchida J, Matsuo K, Takechi T. Tsukihara H, et al. Among authors: okabe h. Oncol Rep. 2015 May;33(5):2135-42. doi: 10.3892/or.2015.3876. Epub 2015 Mar 23. Oncol Rep. 2015. PMID: 25812794 Free PMC article.

2

Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts.

Takechi T, Okabe H, Ikeda K, Fujioka A, Nakagawa F, Ohshimo H, Kitazato K, Fukushima M. Takechi T, et al. Among authors: okabe h. Oncol Rep. 2005 Jul;14(1):33-9. Oncol Rep. 2005. PMID: 15944764

3

Contrasting effects of extended low dose versus standard dose shorter course UFT chemotherapy on microscopic versus macroscopic established tumors: implications for optimal postoperative adjuvant chemotherapy.

Uchida J, Okabe H, Nakano K, Fujioka A, Saito H, Sugimoto Y, Oka T, Fukushima M. Uchida J, et al. Among authors: okabe h. Oncol Rep. 2007 Aug;18(2):313-9. Oncol Rep. 2007. PMID: 17611650

4

Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models.

Tanaka N, Sakamoto K, Okabe H, Fujioka A, Yamamura K, Nakagawa F, Nagase H, Yokogawa T, Oguchi K, Ishida K, Osada A, Kazuno H, Yamada Y, Matsuo K. Tanaka N, et al. Among authors: okabe h. Oncol Rep. 2014 Dec;32(6):2319-26. doi: 10.3892/or.2014.3487. Epub 2014 Sep 17. Oncol Rep. 2014. PMID: 25230742 Free PMC article.

5

Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA.

Sakamoto K, Yokogawa T, Ueno H, Oguchi K, Kazuno H, Ishida K, Tanaka N, Osada A, Yamada Y, Okabe H, Matsuo K. Sakamoto K, et al. Among authors: okabe h. Int J Oncol. 2015;46(6):2327-34. doi: 10.3892/ijo.2015.2974. Epub 2015 Apr 20. Int J Oncol. 2015. PMID: 25901475 Free PMC article.

6

Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells.

Matsuoka K, Nakagawa F, Tanaka N, Okabe H, Matsuo K, Takechi T. Matsuoka K, et al. Among authors: okabe h. Int J Mol Sci. 2018 Sep 25;19(10):2915. doi: 10.3390/ijms19102915. Int J Mol Sci. 2018. PMID: 30257515 Free PMC article.

7

An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA.

Emura T, Nakagawa F, Fujioka A, Ohshimo H, Yokogawa T, Okabe H, Kitazato K. Emura T, et al. Among authors: okabe h. Int J Mol Med. 2004 Feb;13(2):249-55. Int J Mol Med. 2004. PMID: 14719131

8

Sensitivity of human cancer cells to the new anticancer ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2.

Shimamoto Y, Koizumi K, Okabe H, Kazuno H, Murakami Y, Nakagawa F, Matsuda A, Sasaki T, Fukushima M. Shimamoto Y, et al. Among authors: okabe h. Jpn J Cancer Res. 2002 Jul;93(7):825-33. doi: 10.1111/j.1349-7006.2002.tb01325.x. Jpn J Cancer Res. 2002. PMID: 12149149 Free PMC article.

9

Induction of thymidine phosphorylase by interferon and taxanes occurs only in human cancer cells with low thymidine phosphorylase activity.

Fukushima M, Okabe H, Takechi T, Ichikawa W, Hirayama R. Fukushima M, et al. Among authors: okabe h. Cancer Lett. 2002 Dec 10;187(1-2):103-10. doi: 10.1016/s0304-3835(02)00358-0. Cancer Lett. 2002. PMID: 12359357

10

A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma.

Iwata H, Sato H, Suzuki R, Yamada R, Ichinomiya S, Yanagihara M, Okabe H, Sekine Y, Yano T, Ueno K. Iwata H, et al. Among authors: okabe h. Int J Oncol. 2011 Jun;38(6):1653-61. doi: 10.3892/ijo.2011.999. Epub 2011 Apr 6. Int J Oncol. 2011. PMID: 21479360

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