Sakamoto K - Search Results

1

Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts.

Tsukihara H, Nakagawa F, Sakamoto K, Ishida K, Tanaka N, Okabe H, Uchida J, Matsuo K, Takechi T. Tsukihara H, et al. Among authors: sakamoto k. Oncol Rep. 2015 May;33(5):2135-42. doi: 10.3892/or.2015.3876. Epub 2015 Mar 23. Oncol Rep. 2015. PMID: 25812794 Free PMC article.

2

Irinotecan overcomes the resistance to 5-fluorouracil in human colon cancer xenografts by down-regulation of intratumoral thymidylate synthase.

Fukushima M, Sakamoto K, Ohshimo H, Nakagawa F, Taguchi T. Fukushima M, et al. Among authors: sakamoto k. Oncol Rep. 2010 Oct;24(4):835-42. doi: 10.3892/or.2010.835. Oncol Rep. 2010. PMID: 20811661

3

Gimeracil, a component of S-1, may enhance the antitumor activity of X-ray irradiation in human cancer xenograft models in vivo.

Fukushima M, Sakamoto K, Sakata M, Nakagawa F, Saito H, Sakata Y. Fukushima M, et al. Among authors: sakamoto k. Oncol Rep. 2010 Nov;24(5):1307-13. doi: 10.3892/or_00000987. Oncol Rep. 2010. PMID: 20878125

4

Efficacy of combination chemotherapy using oral fluoropyrimidine S-1 with oxaliplatin (SOX) against colorectal cancer in vivo.

Nukatsuka M, Saito H, Sakamoto K, Nakagawa F, Uchida J, Kobunai T, Shiraishi K, Takechi T. Nukatsuka M, et al. Among authors: sakamoto k. Anticancer Res. 2012 Jul;32(7):2807-12. Anticancer Res. 2012. PMID: 22753741

5

Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models.

Tanaka N, Sakamoto K, Okabe H, Fujioka A, Yamamura K, Nakagawa F, Nagase H, Yokogawa T, Oguchi K, Ishida K, Osada A, Kazuno H, Yamada Y, Matsuo K. Tanaka N, et al. Among authors: sakamoto k. Oncol Rep. 2014 Dec;32(6):2319-26. doi: 10.3892/or.2014.3487. Epub 2014 Sep 17. Oncol Rep. 2014. PMID: 25230742 Free PMC article.

6

Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA.

Sakamoto K, Yokogawa T, Ueno H, Oguchi K, Kazuno H, Ishida K, Tanaka N, Osada A, Yamada Y, Okabe H, Matsuo K. Sakamoto K, et al. Int J Oncol. 2015;46(6):2327-34. doi: 10.3892/ijo.2015.2974. Epub 2015 Apr 20. Int J Oncol. 2015. PMID: 25901475 Free PMC article.

7

Effect of leucovorin on the antitumor efficacy of the 5-FU prodrug, tegafur-uracil, in human colorectal cancer xenografts with various expression levels of thymidylate synthase.

Tsujimoto H, Tsukioka S, Ono S, Sakamoto E, Sakamoto K, Tsuta K, Nakagawa F, Saito H, Uchida J, Kiniwa M, Fukushima M. Tsujimoto H, et al. Among authors: sakamoto k, sakamoto e. Oncol Lett. 2010 Nov;1(6):973-980. doi: 10.3892/ol.2010.172. Epub 2010 Sep 17. Oncol Lett. 2010. PMID: 22870097 Free PMC article.

8

Combination therapy using oral S-1 and targeted agents against human tumor xenografts in nude mice.

Nukatsuka M, Saito H, Nakagawa F, Tsujimoto H, Sakamoto K, Tsukioka S, Uchida J, Kiniwa M, Kobunai T, Takechi T. Nukatsuka M, et al. Among authors: sakamoto k. Exp Ther Med. 2012 May;3(5):755-762. doi: 10.3892/etm.2012.484. Epub 2012 Feb 13. Exp Ther Med. 2012. PMID: 22969964 Free PMC article.

9

Panitumumab in combination with irinotecan plus S-1 (IRIS) as second-line therapy for metastatic colorectal cancer.

Takaoka T, Kimura T, Shimoyama R, Kawamoto S, Sakamoto K, Goda F, Miyamoto H, Negoro Y, Tsuji A, Yoshizaki K, Goji T, Kitamura S, Yano H, Okamoto K, Kimura M, Okahisa T, Muguruma N, Niitsu Y, Takayama T. Takaoka T, et al. Among authors: sakamoto k. Cancer Chemother Pharmacol. 2016 Aug;78(2):397-403. doi: 10.1007/s00280-016-3096-5. Epub 2016 Jun 24. Cancer Chemother Pharmacol. 2016. PMID: 27342247 Clinical Trial.

10

Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.

Kazuno H, Sakamoto K, Fujioka A, Fukushima M, Matsuda A, Sasaki T. Kazuno H, et al. Among authors: sakamoto k. Cancer Sci. 2005 May;96(5):295-302. doi: 10.1111/j.1349-7006.2005.00046.x. Cancer Sci. 2005. PMID: 15904471 Free PMC article.

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