Hofker MH - Search Results

1

Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice.

Hendrikx T, Jeurissen ML, van Gorp PJ, Gijbels MJ, Walenbergh SM, Houben T, van Gorp R, Pöttgens CC, Stienstra R, Netea MG, Hofker MH, Donners MM, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: hofker mh. FEBS J. 2015 Jun;282(12):2327-38. doi: 10.1111/febs.13279. Epub 2015 Apr 20. FEBS J. 2015. PMID: 25817537 Free article.

2

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.

Wouters K, van Bilsen M, van Gorp PJ, Bieghs V, Lütjohann D, Kerksiek A, Staels B, Hofker MH, Shiri-Sverdlov R. Wouters K, et al. Among authors: hofker mh. FEBS Lett. 2010 Mar 5;584(5):1001-5. doi: 10.1016/j.febslet.2010.01.046. Epub 2010 Jan 29. FEBS Lett. 2010. PMID: 20114046 Free article.

3

Bone marrow transplantation as an established approach for understanding the role of macrophages in atherosclerosis and the metabolic syndrome.

Aparicio-Vergara M, Shiri-Sverdlov R, Koonen DP, Hofker MH. Aparicio-Vergara M, et al. Among authors: hofker mh. Curr Opin Lipidol. 2012 Apr;23(2):111-21. doi: 10.1097/MOL.0b013e3283508c4f. Curr Opin Lipidol. 2012. PMID: 22274753 Review.

4

LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease.

Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: hofker mh. PLoS One. 2012;7(1):e30668. doi: 10.1371/journal.pone.0030668. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295101 Free PMC article.

5

Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice.

Hendrikx T, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Jeurissen ML, Steinbusch MM, Vaes N, Binder CJ, Koek GH, Stienstra R, Netea MG, Hofker MH, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: hofker mh. PLoS One. 2013 Dec 2;8(12):e78792. doi: 10.1371/journal.pone.0078792. eCollection 2013. PLoS One. 2013. PMID: 24312444 Free PMC article.

6

Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.

Hendrikx T, Jeurissen ML, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Houben T, Guichot YD, Gijbels MJ, Leitersdorf E, Hofker MH, Lütjohann D, Shiri-Sverdlov R. Hendrikx T, et al. Among authors: hofker mh. J Hepatol. 2015 Feb;62(2):430-6. doi: 10.1016/j.jhep.2014.09.027. Epub 2014 Oct 2. J Hepatol. 2015. PMID: 25281859

7

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis.

Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, van Bilsen M, Shiri-Sverdlov R, Hofker MH. Wouters K, et al. Among authors: hofker mh. Hepatology. 2008 Aug;48(2):474-86. doi: 10.1002/hep.22363. Hepatology. 2008. PMID: 18666236

8

Bone marrow transplantation in mice as a tool for studying the role of hematopoietic cells in metabolic and cardiovascular diseases.

Aparicio-Vergara M, Shiri-Sverdlov R, de Haan G, Hofker MH. Aparicio-Vergara M, et al. Among authors: hofker mh. Atherosclerosis. 2010 Dec;213(2):335-44. doi: 10.1016/j.atherosclerosis.2010.05.030. Epub 2010 Jun 1. Atherosclerosis. 2010. PMID: 20576267 Review.

9

NASH and atherosclerosis are two aspects of a shared disease: central role for macrophages.

Bieghs V, Rensen PC, Hofker MH, Shiri-Sverdlov R. Bieghs V, et al. Among authors: hofker mh. Atherosclerosis. 2012 Feb;220(2):287-93. doi: 10.1016/j.atherosclerosis.2011.08.041. Epub 2011 Sep 3. Atherosclerosis. 2012. PMID: 21930273 Review.

10

Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice.

Bieghs V, van Gorp PJ, Walenbergh SM, Gijbels MJ, Verheyen F, Buurman WA, Briles DE, Hofker MH, Binder CJ, Shiri-Sverdlov R. Bieghs V, et al. Among authors: hofker mh. Hepatology. 2012 Sep;56(3):894-903. doi: 10.1002/hep.25660. Epub 2012 Jul 6. Hepatology. 2012. PMID: 22334337 Free PMC article.

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