Kombairaju P - Search Results

1

Knockout of the transcription factor Nrf2: Effects on testosterone production by aging mouse Leydig cells.

Chen H, Jin S, Guo J, Kombairaju P, Biswal S, Zirkin BR. Chen H, et al. Among authors: kombairaju p. Mol Cell Endocrinol. 2015 Jul 5;409:113-20. doi: 10.1016/j.mce.2015.03.013. Epub 2015 Mar 25. Mol Cell Endocrinol. 2015. PMID: 25818884 Free PMC article.

2

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice.

Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S. Sussan TE, et al. Among authors: kombairaju p. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):250-5. doi: 10.1073/pnas.0804333106. Epub 2008 Dec 22. Proc Natl Acad Sci U S A. 2009. PMID: 19104057 Free PMC article.

3

Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation.

Blake DJ, Singh A, Kombairaju P, Malhotra D, Mariani TJ, Tuder RM, Gabrielson E, Biswal S. Blake DJ, et al. Among authors: kombairaju p. Am J Respir Cell Mol Biol. 2010 May;42(5):524-36. doi: 10.1165/rcmb.2009-0054OC. Epub 2009 Jun 11. Am J Respir Cell Mol Biol. 2010. PMID: 19520915 Free PMC article.

4

NADPH oxidase-dependent reactive oxygen species mediate amplified TLR4 signaling and sepsis-induced mortality in Nrf2-deficient mice.

Kong X, Thimmulappa R, Kombairaju P, Biswal S. Kong X, et al. Among authors: kombairaju p. J Immunol. 2010 Jul 1;185(1):569-77. doi: 10.4049/jimmunol.0902315. Epub 2010 May 28. J Immunol. 2010. PMID: 20511556 Free PMC article.

5

Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis.

Kong X, Thimmulappa R, Craciun F, Harvey C, Singh A, Kombairaju P, Reddy SP, Remick D, Biswal S. Kong X, et al. Among authors: kombairaju p. Am J Respir Crit Care Med. 2011 Oct 15;184(8):928-38. doi: 10.1164/rccm.201102-0271OC. Epub 2011 Jul 28. Am J Respir Crit Care Med. 2011. PMID: 21799073 Free PMC article.

6

Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth.

Zhang P, Singh A, Yegnasubramanian S, Esopi D, Kombairaju P, Bodas M, Wu H, Bova SG, Biswal S. Zhang P, et al. Among authors: kombairaju p. Mol Cancer Ther. 2010 Feb;9(2):336-46. doi: 10.1158/1535-7163.MCT-09-0589. Epub 2010 Feb 2. Mol Cancer Ther. 2010. PMID: 20124447 Free PMC article.

7

Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients.

Malhotra D, Thimmulappa RK, Mercado N, Ito K, Kombairaju P, Kumar S, Ma J, Feller-Kopman D, Wise R, Barnes P, Biswal S. Malhotra D, et al. Among authors: kombairaju p. J Clin Invest. 2011 Nov;121(11):4289-302. doi: 10.1172/JCI45144. Epub 2011 Oct 17. J Clin Invest. 2011. Retraction in: J Clin Invest. 2014 Dec;124(12):5521. doi: 10.1172/JCI79606. PMID: 22005302 Free PMC article. Retracted.

8

Prolonged sulforaphane treatment does not enhance tumorigenesis in oncogenic K-ras and xenograft mouse models of lung cancer.

Kombairaju P, Ma J, Thimmulappa RK, Yan SG, Gabrielson E, Singh A, Biswal S. Kombairaju P, et al. J Carcinog. 2012;11:8. doi: 10.4103/1477-3163.98459. Epub 2012 Jul 13. J Carcinog. 2012. PMID: 22919281 Free PMC article.

9

Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle.

Kombairaju P, Kerr JP, Roche JA, Pratt SJP, Lovering RM, Sussan TE, Kim JH, Shi G, Biswal S, Ward CW. Kombairaju P, et al. Front Physiol. 2014 Feb 19;5:57. doi: 10.3389/fphys.2014.00057. eCollection 2014. Front Physiol. 2014. PMID: 24600403 Free PMC article.

10

NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation.

Kim JH, Thimmulappa RK, Kumar V, Cui W, Kumar S, Kombairaju P, Zhang H, Margolick J, Matsui W, Macvittie T, Malhotra SV, Biswal S. Kim JH, et al. Among authors: kombairaju p. J Clin Invest. 2014 Feb;124(2):730-41. doi: 10.1172/JCI70812. Epub 2014 Jan 27. J Clin Invest. 2014. PMID: 24463449 Free PMC article.

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