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Page 1
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.
Harre U, Lang SC, Pfeifle R, Rombouts Y, Frühbeißer S, Amara K, Bang H, Lux A, Koeleman CA, Baum W, Dietel K, Gröhn F, Malmström V, Klareskog L, Krönke G, Kocijan R, Nimmerjahn F, Toes RE, Herrmann M, Scherer HU, Schett G. Harre U, et al. Among authors: koeleman ca. Nat Commun. 2015 Mar 31;6:6651. doi: 10.1038/ncomms7651. Nat Commun. 2015. PMID: 25825024 Free PMC article.
Fc-glycosylation of IgG1 is modulated by B-cell stimuli.
Wang J, Balog CI, Stavenhagen K, Koeleman CA, Scherer HU, Selman MH, Deelder AM, Huizinga TW, Toes RE, Wuhrer M. Wang J, et al. Among authors: koeleman ca. Mol Cell Proteomics. 2011 May;10(5):M110.004655. doi: 10.1074/mcp.M110.004655. Epub 2011 Mar 3. Mol Cell Proteomics. 2011. PMID: 21372248 Free PMC article.
Site-specific N-glycosylation analysis of human immunoglobulin e.
Plomp R, Hensbergen PJ, Rombouts Y, Zauner G, Dragan I, Koeleman CA, Deelder AM, Wuhrer M. Plomp R, et al. Among authors: koeleman ca. J Proteome Res. 2014 Feb 7;13(2):536-46. doi: 10.1021/pr400714w. Epub 2013 Dec 13. J Proteome Res. 2014. PMID: 24308486
Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3).
Plomp R, Dekkers G, Rombouts Y, Visser R, Koeleman CA, Kammeijer GS, Jansen BC, Rispens T, Hensbergen PJ, Vidarsson G, Wuhrer M. Plomp R, et al. Among authors: koeleman ca. Mol Cell Proteomics. 2015 May;14(5):1373-84. doi: 10.1074/mcp.M114.047381. Epub 2015 Mar 10. Mol Cell Proteomics. 2015. PMID: 25759508 Free PMC article.
N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.
Holst S, Deuss AJ, van Pelt GW, van Vliet SJ, Garcia-Vallejo JJ, Koeleman CA, Deelder AM, Mesker WE, Tollenaar RA, Rombouts Y, Wuhrer M. Holst S, et al. Among authors: koeleman ca. Mol Cell Proteomics. 2016 Jan;15(1):124-40. doi: 10.1074/mcp.M115.051235. Epub 2015 Nov 4. Mol Cell Proteomics. 2016. PMID: 26537799 Free PMC article.
Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.
Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G. Pfeifle R, et al. Among authors: koeleman ca. Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7. Nat Immunol. 2017. PMID: 27820809 Free PMC article.
IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Steffen U, Koeleman CA, Sokolova MV, Bang H, Kleyer A, Rech J, Unterweger H, Schicht M, Garreis F, Hahn J, Andes FT, Hartmann F, Hahn M, Mahajan A, Paulsen F, Hoffmann M, Lochnit G, Muñoz LE, Wuhrer M, Falck D, Herrmann M, Schett G. Steffen U, et al. Among authors: koeleman ca. Nat Commun. 2020 Jan 8;11(1):120. doi: 10.1038/s41467-019-13992-8. Nat Commun. 2020. PMID: 31913287 Free PMC article.
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.
Kissel T, Ge C, Hafkenscheid L, Kwekkeboom JC, Slot LM, Cavallari M, He Y, van Schie KA, Vergroesen RD, Kampstra ASB, Reijm S, Stoeken-Rijsbergen G, Koeleman C, Voortman LM, Heitman LH, Xu B, Pruijn GJM, Wuhrer M, Rispens T, Huizinga TWJ, Scherer HU, Reth M, Holmdahl R, Toes REM. Kissel T, et al. Sci Adv. 2022 Feb 11;8(6):eabm1759. doi: 10.1126/sciadv.abm1759. Epub 2022 Feb 9. Sci Adv. 2022. PMID: 35138894 Free PMC article.
IgG Fab Glycans Hinder FcRn-Mediated Placental Transport.
Volkov M, Brinkhaus M, van Schie KA, Bondt A, Kissel T, van der Kooi EJ, Bentlage AEH, Koeleman CAM, de Taeye SW, Derksen NI, Dolhain RJEM, Braig-Scherer U, Huizinga TWJ, Wuhrer M, Toes REM, Vidarsson G, van der Woude D. Volkov M, et al. Among authors: koeleman cam. J Immunol. 2023 Jan 15;210(2):158-167. doi: 10.4049/jimmunol.2200438. J Immunol. 2023. PMID: 36480251
92 results