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Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1.
Seillier M, Pouyet L, N'Guessan P, Nollet M, Capo F, Guillaumond F, Peyta L, Dumas JF, Varrault A, Bertrand G, Bonnafous S, Tran A, Meur G, Marchetti P, Ravier MA, Dalle S, Gual P, Muller D, Rutter GA, Servais S, Iovanna JL, Carrier A. Seillier M, et al. Among authors: guillaumond f. EMBO Mol Med. 2015 Jun;7(6):802-18. doi: 10.15252/emmm.201404318. EMBO Mol Med. 2015. PMID: 25828351 Free PMC article.
Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, Lac S, Borge L, Roques J, Gayet O, Pinault M, Guimaraes C, Nigri J, Loncle C, Lavaut MN, Garcia S, Tailleux A, Staels B, Calvo E, Tomasini R, Iovanna JL, Vasseur S. Guillaumond F, et al. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2473-8. doi: 10.1073/pnas.1421601112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675507 Free PMC article.
Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.
Gouirand V, Gicquel T, Lien EC, Jaune-Pons E, Da Costa Q, Finetti P, Metay E, Duluc C, Mayers JR, Audebert S, Camoin L, Borge L, Rubis M, Leca J, Nigri J, Bertucci F, Dusetti N, Iovanna JL, Tomasini R, Bidaut G, Guillaumond F, Vander Heiden MG, Vasseur S. Gouirand V, et al. Among authors: guillaumond f. EMBO J. 2022 May 2;41(9):e110466. doi: 10.15252/embj.2021110466. Epub 2022 Mar 21. EMBO J. 2022. PMID: 35307861 Free PMC article.
Combining the antianginal drug perhexiline with chemotherapy induces complete pancreatic cancer regression in vivo.
Reyes-Castellanos G, Abdel Hadi N, Gallardo-Arriaga S, Masoud R, Garcia J, Lac S, El Kaoutari A, Gicquel T, Planque M, Fendt SM, Linares LK, Gayet O, Guillaumond F, Dusetti N, Iovanna J, Carrier A. Reyes-Castellanos G, et al. Among authors: guillaumond f. iScience. 2023 May 19;26(6):106899. doi: 10.1016/j.isci.2023.106899. eCollection 2023 Jun 16. iScience. 2023. PMID: 37305702 Free PMC article.
Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling.
Secq V, Leca J, Bressy C, Guillaumond F, Skrobuk P, Nigri J, Lac S, Lavaut MN, Bui TT, Thakur AK, Callizot N, Steinschneider R, Berthezene P, Dusetti N, Ouaissi M, Moutardier V, Calvo E, Bousquet C, Garcia S, Bidaut G, Vasseur S, Iovanna JL, Tomasini R. Secq V, et al. Among authors: guillaumond f. Cell Death Dis. 2015 Jan 15;6(1):e1592. doi: 10.1038/cddis.2014.557. Cell Death Dis. 2015. PMID: 25590802 Free PMC article.
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