Chovan JP - Search Results

1

Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites.

Darwish M, Bond M, Hellriegel E, Robertson P Jr, Chovan JP. Darwish M, et al. Among authors: chovan jp. Cancer Chemother Pharmacol. 2015 Jun;75(6):1143-54. doi: 10.1007/s00280-015-2727-6. Epub 2015 Apr 1. Cancer Chemother Pharmacol. 2015. PMID: 25829094 Free PMC article. Review.

2

Metabolic profile of [(14)C]bendamustine in rat urine and bile: preliminary structural identification of metabolites.

Chovan JP, Li F, Yu E, Ring SC. Chovan JP, et al. Drug Metab Dispos. 2007 Oct;35(10):1744-53. doi: 10.1124/dmd.107.015958. Epub 2007 Jun 28. Drug Metab Dispos. 2007. PMID: 17600082

3

Identification of imine or enamine drug metabolites using online hydrogen/deuterium exchange and exact mass measurements.

Li AC, Yu E, Ring SC, Chovan JP. Li AC, et al. Among authors: chovan jp. Rapid Commun Mass Spectrom. 2012 Apr 30;26(8):906-14. doi: 10.1002/rcm.6178. Rapid Commun Mass Spectrom. 2012. PMID: 22396026

4

Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite.

Li AC, Chovan JP, Yu E, Zamora I. Li AC, et al. Among authors: chovan jp. Xenobiotica. 2013 Apr;43(4):390-8. doi: 10.3109/00498254.2012.715697. Epub 2012 Aug 30. Xenobiotica. 2013. PMID: 22931213

5

Structural identification of imatinib cyanide adducts by mass spectrometry and elucidation of bioactivation pathway.

Li AC, Yu E, Ring SC, Chovan JP. Li AC, et al. Among authors: chovan jp. Rapid Commun Mass Spectrom. 2014 Jan 15;28(1):123-34. doi: 10.1002/rcm.6758. Rapid Commun Mass Spectrom. 2014. PMID: 24285397

6

Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats.

Chovan JP, Ring SC, Yu E, Baldino JP. Chovan JP, et al. Xenobiotica. 2007 May;37(5):459-73. doi: 10.1080/00498250701245250. Xenobiotica. 2007. PMID: 17523050

7

Boronic acid-containing proteasome inhibitors: alert to potential pharmaceutical bioactivation.

Li AC, Yu E, Ring SC, Chovan JP. Li AC, et al. Among authors: chovan jp. Chem Res Toxicol. 2013 Apr 15;26(4):608-15. doi: 10.1021/tx400032n. Epub 2013 Apr 2. Chem Res Toxicol. 2013. PMID: 23514361

8

Development of tolerance to the antihypertensive effects of highly selective adenosine A2a agonists upon chronic administration.

Webb RL, Sills MA, Chovan JP, Peppard JV, Francis JE. Webb RL, et al. Among authors: chovan jp. J Pharmacol Exp Ther. 1993 Oct;267(1):287-95. J Pharmacol Exp Ther. 1993. PMID: 8229754

9

Automated-extraction, high-performance liquid chromatographic method and pharmacokinetics in rats of a highly A2-selective adenosine agonist, CGS 21680.

Chovan JP, Zane PA, Greenberg GE. Chovan JP, et al. J Chromatogr. 1992 Jul 1;578(1):77-83. doi: 10.1016/0378-4347(92)80227-h. J Chromatogr. 1992. PMID: 1400789

10

High-performance liquid chromatographic method for a clozapine analogue, CGS 13429, and its N-oxide and desmethyl metabolites.

Chovan JP, Vermeulen JD. Chovan JP, et al. J Chromatogr. 1989 Sep 29;494:413-9. doi: 10.1016/s0378-4347(00)82697-3. J Chromatogr. 1989. PMID: 2573611 No abstract available.

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