Philipson LH - Search Results

1

Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A.

Rajan S, Dickson LM, Mathew E, Orr CM, Ellenbroek JH, Philipson LH, Wicksteed B. Rajan S, et al. Among authors: philipson lh. Mol Metab. 2015 Feb 3;4(4):265-76. doi: 10.1016/j.molmet.2015.01.010. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830090 Free PMC article.

2

Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.

Hays LB, Wicksteed B, Wang Y, McCuaig JF, Philipson LH, Edwardson JM, Rhodes CJ. Hays LB, et al. Among authors: philipson lh. J Endocrinol. 2005 Apr;185(1):57-67. doi: 10.1677/joe.1.05934. J Endocrinol. 2005. PMID: 15817827

3

The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing.

Jacobson DA, Wicksteed BL, Philipson LH. Jacobson DA, et al. Among authors: philipson lh. Diabetes. 2009 Feb;58(2):304-6. doi: 10.2337/db08-1618. Diabetes. 2009. PMID: 19171747 Free PMC article. No abstract available.

4

In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.

Rajan S, Eames SC, Park SY, Labno C, Bell GI, Prince VE, Philipson LH. Rajan S, et al. Among authors: philipson lh. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E403-10. doi: 10.1152/ajpendo.00592.2009. Epub 2009 Dec 1. Am J Physiol Endocrinol Metab. 2010. PMID: 19952343 Free PMC article.

5

Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.

Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG Jr, Gannon M, Powers AC, Dempsey PJ. Wicksteed B, et al. Among authors: philipson lh. Diabetes. 2010 Dec;59(12):3090-8. doi: 10.2337/db10-0624. Epub 2010 Aug 29. Diabetes. 2010. PMID: 20802254 Free PMC article.

6

SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion.

Rajan S, Torres J, Thompson MS, Philipson LH. Rajan S, et al. Among authors: philipson lh. Am J Physiol Endocrinol Metab. 2012 Mar 15;302(6):E714-23. doi: 10.1152/ajpendo.00486.2011. Epub 2012 Jan 10. Am J Physiol Endocrinol Metab. 2012. PMID: 22234371 Free PMC article.

7

β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion.

Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B. Kaihara KA, et al. Among authors: philipson lh. Diabetes. 2013 May;62(5):1527-36. doi: 10.2337/db12-1013. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349500 Free PMC article.

8

The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs.

Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA. Smith EP, et al. Among authors: philipson lh. Cell Metab. 2014 Jun 3;19(6):1050-7. doi: 10.1016/j.cmet.2014.04.005. Epub 2014 May 15. Cell Metab. 2014. PMID: 24836562 Free PMC article.

9

Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells.

Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN. Liew CW, et al. Among authors: philipson lh. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2319-28. doi: 10.1073/pnas.1323066111. Epub 2014 May 19. Proc Natl Acad Sci U S A. 2014. PMID: 24843127 Free PMC article.

10

Transgenic zebrafish model of the C43G human insulin gene mutation.

Eames SC, Kinkel MD, Rajan S, Prince VE, Philipson LH. Eames SC, et al. Among authors: philipson lh. J Diabetes Investig. 2013 Mar 18;4(2):157-67. doi: 10.1111/jdi.12015. Epub 2012 Nov 5. J Diabetes Investig. 2013. PMID: 24843647 Free PMC article.

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