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273 results

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mTORC2 regulates cardiac response to stress by inhibiting MST1.
Sciarretta S, Zhai P, Maejima Y, Del Re DP, Nagarajan N, Yee D, Liu T, Magnuson MA, Volpe M, Frati G, Li H, Sadoshima J. Sciarretta S, et al. Among authors: nagarajan n. Cell Rep. 2015 Apr 7;11(1):125-36. doi: 10.1016/j.celrep.2015.03.010. Epub 2015 Apr 2. Cell Rep. 2015. PMID: 25843706 Free PMC article.
Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating transcription factor 4 pathway.
Sciarretta S, Zhai P, Shao D, Zablocki D, Nagarajan N, Terada LS, Volpe M, Sadoshima J. Sciarretta S, et al. Among authors: nagarajan n. Circ Res. 2013 Nov 8;113(11):1253-64. doi: 10.1161/CIRCRESAHA.113.301787. Epub 2013 Sep 30. Circ Res. 2013. PMID: 24081881 Free PMC article.
The importance of autophagy in cardioprotection.
Sciarretta S, Yee D, Shenoy V, Nagarajan N, Sadoshima J. Sciarretta S, et al. Among authors: nagarajan n. High Blood Press Cardiovasc Prev. 2014 Mar;21(1):21-8. doi: 10.1007/s40292-013-0029-9. Epub 2013 Nov 14. High Blood Press Cardiovasc Prev. 2014. PMID: 24235024 Review.
Identification of novel nuclear targets of human thioredoxin 1.
Wu C, Jain MR, Li Q, Oka S, Li W, Kong AN, Nagarajan N, Sadoshima J, Simmons WJ, Li H. Wu C, et al. Among authors: nagarajan n. Mol Cell Proteomics. 2014 Dec;13(12):3507-18. doi: 10.1074/mcp.M114.040931. Epub 2014 Sep 17. Mol Cell Proteomics. 2014. PMID: 25231459 Free PMC article.
Master redox regulator Trx1 upregulates SMYD1 & modulates lysine methylation.
Liu T, Wu C, Jain MR, Nagarajan N, Yan L, Dai H, Cui C, Baykal A, Pan S, Ago T, Sadoshima J, Li H. Liu T, et al. Among authors: nagarajan n. Biochim Biophys Acta. 2015 Dec;1854(12):1816-1822. doi: 10.1016/j.bbapap.2015.09.006. Epub 2015 Sep 26. Biochim Biophys Acta. 2015. PMID: 26410624 Free PMC article.
Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.
Matsushima S, Kuroda J, Zhai P, Liu T, Ikeda S, Nagarajan N, Oka S, Yokota T, Kinugawa S, Hsu CP, Li H, Tsutsui H, Sadoshima J. Matsushima S, et al. Among authors: nagarajan n. J Clin Invest. 2016 Sep 1;126(9):3403-16. doi: 10.1172/JCI85624. Epub 2016 Aug 15. J Clin Invest. 2016. PMID: 27525436 Free PMC article.
273 results