Saliba KJ - Search Results

1

A pantetheinase-resistant pantothenamide with potent, on-target, and selective antiplasmodial activity.

Macuamule CJ, Tjhin ET, Jana CE, Barnard L, Koekemoer L, de Villiers M, Saliba KJ, Strauss E. Macuamule CJ, et al. Among authors: saliba kj. Antimicrob Agents Chemother. 2015;59(6):3666-8. doi: 10.1128/AAC.04970-14. Epub 2015 Apr 6. Antimicrob Agents Chemother. 2015. PMID: 25845876 Free PMC article.

2

Chloroquine resistance and the pH of the malaria parasite's digestive vacuole.

Kirk K, Saliba KJ. Kirk K, et al. Among authors: saliba kj. Drug Resist Updat. 2001 Dec;4(6):335-7. doi: 10.1054/drup.2002.0234. Drug Resist Updat. 2001. PMID: 12030781

3

Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite.

Saliba KJ, Ferru I, Kirk K. Saliba KJ, et al. Antimicrob Agents Chemother. 2005 Feb;49(2):632-7. doi: 10.1128/AAC.49.2.632-637.2005. Antimicrob Agents Chemother. 2005. PMID: 15673744 Free PMC article.

4

Mutations in pfmdr1 modulate the sensitivity of Plasmodium falciparum to the intrinsic antiplasmodial activity of verapamil.

Hayward R, Saliba KJ, Kirk K. Hayward R, et al. Among authors: saliba kj. Antimicrob Agents Chemother. 2005 Feb;49(2):840-2. doi: 10.1128/AAC.49.2.840-842.2005. Antimicrob Agents Chemother. 2005. PMID: 15673784 Free PMC article.

5

A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites.

Spry C, Chai CL, Kirk K, Saliba KJ. Spry C, et al. Among authors: saliba kj. Antimicrob Agents Chemother. 2005 Nov;49(11):4649-57. doi: 10.1128/AAC.49.11.4649-4657.2005. Antimicrob Agents Chemother. 2005. PMID: 16251308 Free PMC article.

6

The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance.

Hayward R, Saliba KJ, Kirk K. Hayward R, et al. Among authors: saliba kj. J Cell Sci. 2006 Mar 15;119(Pt 6):1016-25. doi: 10.1242/jcs.02795. Epub 2006 Feb 21. J Cell Sci. 2006. PMID: 16492710

7

The inhibitory effect of 2-halo derivatives of D-glucose on glycolysis and on the proliferation of the human malaria parasite Plasmodium falciparum.

van Schalkwyk DA, Priebe W, Saliba KJ. van Schalkwyk DA, et al. Among authors: saliba kj. J Pharmacol Exp Ther. 2008 Nov;327(2):511-7. doi: 10.1124/jpet.108.141929. Epub 2008 Aug 19. J Pharmacol Exp Ther. 2008. PMID: 18713952

8

Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death.

van Schalkwyk DA, Chan XW, Misiano P, Gagliardi S, Farina C, Saliba KJ. van Schalkwyk DA, et al. Among authors: saliba kj. Biochem Pharmacol. 2010 May 1;79(9):1291-9. doi: 10.1016/j.bcp.2009.12.025. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067768

9

Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.

Spry C, van Schalkwyk DA, Strauss E, Saliba KJ. Spry C, et al. Among authors: saliba kj. Infect Disord Drug Targets. 2010 Jun;10(3):200-16. doi: 10.2174/187152610791163390. Infect Disord Drug Targets. 2010. PMID: 20334619 Review.

10

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.

Spry C, Macuamule C, Lin Z, Virga KG, Lee RE, Strauss E, Saliba KJ. Spry C, et al. Among authors: saliba kj. PLoS One. 2013;8(2):e54974. doi: 10.1371/journal.pone.0054974. Epub 2013 Feb 6. PLoS One. 2013. PMID: 23405100 Free PMC article.

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