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Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Theodoulou NH, Bamborough P, Bannister AJ, Becher I, Bit RA, Che KH, Chung CW, Dittmann A, Drewes G, Drewry DH, Gordon L, Grandi P, Leveridge M, Lindon M, Michon AM, Molnar J, Robson SC, Tomkinson NC, Kouzarides T, Prinjha RK, Humphreys PG. Theodoulou NH, et al. Among authors: drewry dh. J Med Chem. 2016 Feb 25;59(4):1425-39. doi: 10.1021/acs.jmedchem.5b00256. Epub 2015 Apr 30. J Med Chem. 2016. PMID: 25856009 Free PMC article.
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
Bashore FM, Marquez AB, Chaikuad A, Howell S, Dunn AS, Beltran AA, Smith JL, Drewry DH, Beltran AS, Axtman AD. Bashore FM, et al. Among authors: drewry dh. Sci Rep. 2023 Apr 14;13(1):6118. doi: 10.1038/s41598-023-32854-4. Sci Rep. 2023. PMID: 37059819 Free PMC article.
CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle.
Negoita F, Addinsall AB, Hellberg K, Bringas CF, Hafen PS, Sermersheim TJ, Agerholm M, Lewis CTA, Ahwazi D, Ling NXY, Larsen JK, Deshmukh AS, Hossain MA, Oakhill JS, Ochala J, Brault JJ, Sankar U, Drewry DH, Scott JW, Witczak CA, Sakamoto K. Negoita F, et al. Among authors: drewry dh. Mol Metab. 2023 Sep;75:101761. doi: 10.1016/j.molmet.2023.101761. Epub 2023 Jun 26. Mol Metab. 2023. PMID: 37380024 Free PMC article.
Illumination of understudied ciliary kinases.
Flax RG, Rosston P, Rocha C, Anderson B, Capener JL, Durcan TM, Drewry DH, Prinos P, Axtman AD. Flax RG, et al. Among authors: drewry dh. Front Mol Biosci. 2024 Mar 8;11:1352781. doi: 10.3389/fmolb.2024.1352781. eCollection 2024. Front Mol Biosci. 2024. PMID: 38523660 Free PMC article. Review.
Convergence on CaMK4: A Key Modulator of Autism-Associated Signaling Pathways in Neurons.
Kaiser J, Risteska A, Muller AG, Sun H, Lei B, Nay K, Means AR, Cousin MA, Drewry DH, Oakhill JS, Kemp BE, Hannan AJ, Berk M, Febbraio MA, Gundlach AL, Hill-Yardin EL, Scott JW. Kaiser J, et al. Among authors: drewry dh. Biol Psychiatry. 2024 Oct 21:S0006-3223(24)01696-2. doi: 10.1016/j.biopsych.2024.10.012. Online ahead of print. Biol Psychiatry. 2024. PMID: 39442785 Free article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 39163320
An open source plant kinase chemogenomics set.
Ercoli MF, Ramos PZ, Jain R, Pilotte J, Dong OX, Thompson T, Wells CI, Elkins JM, Edwards AM, Couñago RM, Drewry DH, Ronald PC. Ercoli MF, et al. Among authors: drewry dh. Plant Direct. 2022 Nov 25;6(11):e460. doi: 10.1002/pld3.460. eCollection 2022 Nov. Plant Direct. 2022. PMID: 36447653 Free PMC article.
LKB1 signaling and patient survival outcomes in hepatocellular carcinoma.
Nguyen K, Hebert K, McConnell E, Cullen N, Cheng T, Awoyode S, Martin E, Chen W, Wu T, Alahari SK, Izadpanah R, Collins-Burow BM, Lee SB, Drewry DH, Burow ME. Nguyen K, et al. Among authors: drewry dh. Pharmacol Res. 2023 Jun;192:106757. doi: 10.1016/j.phrs.2023.106757. Epub 2023 Apr 5. Pharmacol Res. 2023. PMID: 37023992 Free article. Review.
118 results