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Page 1
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G. de Vallière C, et al. Among authors: wagner ca. Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375. Inflamm Bowel Dis. 2015. PMID: 25856770 Free PMC article.
PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons.
Kumar NN, Velic A, Soliz J, Shi Y, Li K, Wang S, Weaver JL, Sen J, Abbott SB, Lazarenko RM, Ludwig MG, Perez-Reyes E, Mohebbi N, Bettoni C, Gassmann M, Suply T, Seuwen K, Guyenet PG, Wagner CA, Bayliss DA. Kumar NN, et al. Among authors: wagner ca. Science. 2015 Jun 12;348(6240):1255-60. doi: 10.1126/science.aaa0922. Epub 2015 Jun 11. Science. 2015. PMID: 26068853 Free PMC article.
The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, Ludwig MG, Okoniewski M, Eloranta JJ, Kullak-Ublick GA, Wagner CA, Rogler G, Seuwen K. de Vallière C, et al. Among authors: wagner ca. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G475-90. doi: 10.1152/ajpgi.00408.2014. Epub 2015 Jul 23. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 26206859 Free article.
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA. de Vallière C, et al. Among authors: wagner ca. Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov. Cell Mol Gastroenterol Hepatol. 2016. PMID: 28174749 Free PMC article.
The Proton-activated Receptor GPR4 Modulates Intestinal Inflammation.
Wang Y, de Vallière C, Imenez Silva PH, Leonardi I, Gruber S, Gerstgrasser A, Melhem H, Weber A, Leucht K, Wolfram L, Hausmann M, Krieg C, Thomasson K, Boyman O, Frey-Wagner I, Rogler G, Wagner CA. Wang Y, et al. Among authors: wagner ca. J Crohns Colitis. 2018 Feb 28;12(3):355-368. doi: 10.1093/ecco-jcc/jjx147. J Crohns Colitis. 2018. PMID: 29136128 Free article.
Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis.
Hutter S, van Haaften WT, Hünerwadel A, Baebler K, Herfarth N, Raselli T, Mamie C, Misselwitz B, Rogler G, Weder B, Dijkstra G, Meier CF, de Vallière C, Weber A, Imenez Silva PH, Wagner CA, Frey-Wagner I, Ruiz PA, Hausmann M. Hutter S, et al. Among authors: wagner ca. J Crohns Colitis. 2018 Nov 15;12(11):1348-1358. doi: 10.1093/ecco-jcc/jjy118. J Crohns Colitis. 2018. PMID: 30165600
Lack of the pH-sensing Receptor TDAG8 [GPR65] in Macrophages Plays a Detrimental Role in Murine Models of Inflammatory Bowel Disease.
Tcymbarevich I, Richards SM, Russo G, Kühn-Georgijevic J, Cosin-Roger J, Baebler K, Lang S, Bengs S, Atrott K, Bettoni C, Gruber S, Frey-Wagner I, Scharl M, Misselwitz B, Wagner CA, Seuwen K, Rogler G, Ruiz PA, Spalinger M, de Vallière C. Tcymbarevich I, et al. Among authors: wagner ca. J Crohns Colitis. 2019 Feb 1;13(2):245-258. doi: 10.1093/ecco-jcc/jjy152. J Crohns Colitis. 2019. PMID: 30535144
The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation.
Tcymbarevich IV, Eloranta JJ, Rossel JB, Obialo N, Spalinger M, Cosin-Roger J, Lang S, Kullak-Ublick GA, Wagner CA, Scharl M, Seuwen K, Ruiz PA, Rogler G, de Vallière C, Misselwitz B; Swiss IBD Cohort Study Group. Tcymbarevich IV, et al. Among authors: wagner ca. BMC Gastroenterol. 2019 Jan 7;19(1):2. doi: 10.1186/s12876-018-0922-8. BMC Gastroenterol. 2019. PMID: 30616622 Free PMC article.
385 results