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Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains.
Stuhlmiller TJ, Miller SM, Zawistowski JS, Nakamura K, Beltran AS, Duncan JS, Angus SP, Collins KA, Granger DA, Reuther RA, Graves LM, Gomez SM, Kuan PF, Parker JS, Chen X, Sciaky N, Carey LA, Earp HS, Jin J, Johnson GL. Stuhlmiller TJ, et al. Among authors: kuan pf. Cell Rep. 2015 Apr 21;11(3):390-404. doi: 10.1016/j.celrep.2015.03.037. Epub 2015 Apr 9. Cell Rep. 2015. PMID: 25865888 Free PMC article.
RhoGDI2 antagonizes ovarian carcinoma growth, invasion and metastasis.
Stevens EV, Banet N, Onesto C, Plachco A, Alan JK, Nikolaishvili-Feinberg N, Midkiff BR, Kuan PF, Liu J, Miller CR, Vigil D, Graves LM, Der CJ. Stevens EV, et al. Among authors: kuan pf. Small GTPases. 2011 Jul;2(4):202-210. doi: 10.4161/sgtp.2.4.17795. Epub 2011 Jul 1. Small GTPases. 2011. PMID: 22145092 Free PMC article.
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer.
Duncan JS, Whittle MC, Nakamura K, Abell AN, Midland AA, Zawistowski JS, Johnson NL, Granger DA, Jordan NV, Darr DB, Usary J, Kuan PF, Smalley DM, Major B, He X, Hoadley KA, Zhou B, Sharpless NE, Perou CM, Kim WY, Gomez SM, Chen X, Jin J, Frye SV, Earp HS, Graves LM, Johnson GL. Duncan JS, et al. Among authors: kuan pf. Cell. 2012 Apr 13;149(2):307-21. doi: 10.1016/j.cell.2012.02.053. Cell. 2012. PMID: 22500798 Free PMC article.
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
Schlegel J, Sambade MJ, Sather S, Moschos SJ, Tan AC, Winges A, DeRyckere D, Carson CC, Trembath DG, Tentler JJ, Eckhardt SG, Kuan PF, Hamilton RL, Duncan LM, Miller CR, Nikolaishvili-Feinberg N, Midkiff BR, Liu J, Zhang W, Yang C, Wang X, Frye SV, Earp HS, Shields JM, Graham DK. Schlegel J, et al. Among authors: kuan pf. J Clin Invest. 2013 May;123(5):2257-67. doi: 10.1172/JCI67816. Epub 2013 Apr 15. J Clin Invest. 2013. PMID: 23585477 Free PMC article.
Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia.
Cooper MJ, Cox NJ, Zimmerman EI, Dewar BJ, Duncan JS, Whittle MC, Nguyen TA, Jones LS, Ghose Roy S, Smalley DM, Kuan PF, Richards KL, Christopherson RI, Jin J, Frye SV, Johnson GL, Baldwin AS, Graves LM. Cooper MJ, et al. Among authors: kuan pf. PLoS One. 2013 Jun 24;8(6):e66755. doi: 10.1371/journal.pone.0066755. Print 2013. PLoS One. 2013. PMID: 23826126 Free PMC article.
Utility of TERT Promoter Mutations for Cutaneous Primary Melanoma Diagnosis.
Thomas NE, Edmiston SN, Tsai YS, Parker JS, Googe PB, Busam KJ, Scott GA, Zedek DC, Parrish EA, Hao H, Slater NA, Pearlstein MV, Frank JS, Kuan PF, Ollila DW, Conway K. Thomas NE, et al. Among authors: kuan pf. Am J Dermatopathol. 2019 Apr;41(4):264-272. doi: 10.1097/DAD.0000000000001259. Am J Dermatopathol. 2019. PMID: 30211730 Free PMC article.
Identification of a Robust Methylation Classifier for Cutaneous Melanoma Diagnosis.
Conway K, Edmiston SN, Parker JS, Kuan PF, Tsai YH, Groben PA, Zedek DC, Scott GA, Parrish EA, Hao H, Pearlstein MV, Frank JS, Carson CC, Wilkerson MD, Zhao X, Slater NA, Moschos SJ, Ollila DW, Thomas NE. Conway K, et al. Among authors: kuan pf. J Invest Dermatol. 2019 Jun;139(6):1349-1361. doi: 10.1016/j.jid.2018.11.024. Epub 2018 Dec 6. J Invest Dermatol. 2019. PMID: 30529013 Free PMC article.
IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma.
Carson CC, Moschos SJ, Edmiston SN, Darr DB, Nikolaishvili-Feinberg N, Groben PA, Zhou X, Kuan PF, Pandey S, Chan KT, Jordan JL, Hao H, Frank JS, Hopkinson DA, Gibbs DC, Alldredge VD, Parrish E, Hanna SC, Berkowitz P, Rubenstein DS, Miller CR, Bear JE, Ollila DW, Sharpless NE, Conway K, Thomas NE. Carson CC, et al. Among authors: kuan pf. Clin Cancer Res. 2015 May 1;21(9):2167-76. doi: 10.1158/1078-0432.CCR-14-1826. Clin Cancer Res. 2015. PMID: 25934889 Free PMC article.
96 results