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Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Shelar S, Shim EH, Brinkley GJ, Kundu A, Carobbio F, Poston T, Tan J, Parekh V, Benson D, Crossman DK, Buckhaults PJ, Rakheja D, Kirkman R, Sato Y, Ogawa S, Dutta S, Velu SE, Emberley E, Pan A, Chen J, Huang T, Absher D, Becker A, Kunick C, Sudarshan S. Shelar S, et al. Among authors: poston t. Clin Cancer Res. 2018 Dec 15;24(24):6433-6446. doi: 10.1158/1078-0432.CCR-18-1727. Epub 2018 Aug 14. Clin Cancer Res. 2018. PMID: 30108105 Free PMC article.
Intranasal immunization with CPAF combined with ADU-S100 induces an effector CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum.
Poston TB, Girardi J, Kim M, Zwarycz P, Polson AG, Yount KS, Hanlan C, Jaras Salas I, Lammert SM, Arroyo D, Bruno T, Wu M, Rozzelle J, Fairman J, Esser-Kahn AP, Darville T. Poston TB, et al. Vaccine. 2025 Jan 1;43(Pt 1):126526. doi: 10.1016/j.vaccine.2024.126526. Epub 2024 Nov 12. Vaccine. 2025. PMID: 39536454 Free article.
Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum.
Poston TB, Girardi J, Kim M, Zwarycz P, Polson AG, Yount K, Hanlan C, Salas IJ, Lammert SM, Arroyo D, Bruno T, Wu M, Rozzelle J, Fairman J, Esser-Kahn A, Darville T. Poston TB, et al. bioRxiv [Preprint]. 2024 Sep 24:2024.09.20.614154. doi: 10.1101/2024.09.20.614154. bioRxiv. 2024. Update in: Vaccine. 2025 Jan 1;43(Pt 1):126526. doi: 10.1016/j.vaccine.2024.126526 PMID: 39386616 Free PMC article. Updated. Preprint.
Chlamydia trachomatis induces low-frequency, sustained CD4 T cell responses in most women, predominantly targeting chlamydial protease-like activity factor, CPAF.
Li Y, Warren JA, Poston TB, Clutton G, Shaw FR, Conrad SZ, Xu Y, Zheng X, Yount KS, O'Connell CM, Wiesenfeld HC, Darville T, Goonetilleke N. Li Y, et al. Among authors: poston tb. J Infect Dis. 2024 Sep 9:jiae443. doi: 10.1093/infdis/jiae443. Online ahead of print. J Infect Dis. 2024. PMID: 39250505
38 results