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Additional treatment with 2-Chloro-2-Deoxyadenosine during consolidation in children with high-risk acute myeloid leukemia does not improve survival.
Creutzig U, Dworzak MN, Zimmermann M, Bourquin JP, Gruhn B, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, Stackelberg AV, Starý J, Reinhardt D. Creutzig U, et al. Among authors: gruhn b. Leukemia. 2015 Nov;29(11):2260-3. doi: 10.1038/leu.2015.94. Epub 2015 Apr 14. Leukemia. 2015. PMID: 25869725 Clinical Trial. No abstract available.
Randomised Introduction of 2-CDA as Intensification during Consolidation for Children with High-risk AML--results from Study AML-BFM 2004.
Creutzig U, Dworzak M, Zimmermann M, Bourquin JP, Gruhn B, Fleischhack G, Graf N, Klingebiel T, Kremens B, Lehrnbecher T, von Neuhoff C, von Stackelberg A, Stray J, Reinhardt D. Creutzig U, et al. Among authors: gruhn b. Klin Padiatr. 2015 May;227(3):116-22. doi: 10.1055/s-0035-1548816. Epub 2015 May 18. Klin Padiatr. 2015. PMID: 25985446 Clinical Trial.
Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.
Rasche M, von Neuhoff C, Dworzak M, Bourquin JP, Bradtke J, Göhring G, Escherich G, Fleischhack G, Graf N, Gruhn B, Haas OA, Klingebiel T, Kremens B, Lehrnbecher T, von Stackelberg A, Tchinda J, Zemanova Z, Thiede C, von Neuhoff N, Zimmermann M, Creutzig U, Reinhardt D. Rasche M, et al. Among authors: gruhn b. Leukemia. 2017 Dec;31(12):2807-2814. doi: 10.1038/leu.2017.121. Epub 2017 Apr 25. Leukemia. 2017. PMID: 28443606 Free PMC article.
Real-time PCR quantification of major Wilms' tumor gene 1 (WT1) isoforms in acute myeloid leukemia, their characteristic expression patterns and possible functional consequences.
Kramarzova K, Stuchly J, Willasch A, Gruhn B, Schwarz J, Cermak J, Machova-Polakova K, Fuchs O, Stary J, Trka J, Boublikova L. Kramarzova K, et al. Among authors: gruhn b. Leukemia. 2012 Sep;26(9):2086-95. doi: 10.1038/leu.2012.76. Epub 2012 Mar 20. Leukemia. 2012. PMID: 22430637
Allo-SCT using BU, CY and melphalan for children with AML in second CR.
Beier R, Albert MH, Bader P, Borkhardt A, Creutzig U, Eyrich M, Ehlert K, Gruhn B, Greil J, Handgretinger R, Holter W, Klingebiel T, Kremens B, Lang P, Mauz-Körholz C, Meisel R, Müller I, Peters C, Reinhardt D, Sedlacek P, Schulz A, Schuster FR, Schrauder A, Strahm B, Sykora KW, Wössmann W, Zimmermann M, Sauer MG. Beier R, et al. Among authors: gruhn b. Bone Marrow Transplant. 2013 May;48(5):651-6. doi: 10.1038/bmt.2012.204. Epub 2012 Oct 29. Bone Marrow Transplant. 2013. PMID: 23103678
Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective.
Bader P, Kreyenberg H, Hoelle W, Dueckers G, Kremens B, Dilloo D, Sykora KW, Niemeyer C, Reinhardt D, Vormoor J, Gruhn B, Lang P, Greil J, Handgretinger R, Niethammer D, Klingebiel T, Beck JF. Bader P, et al. Among authors: gruhn b. Bone Marrow Transplant. 2004 Apr;33(8):815-21. doi: 10.1038/sj.bmt.1704444. Bone Marrow Transplant. 2004. PMID: 14990984 Clinical Trial.
Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study.
Willasch AM, Gruhn B, Coliva T, Kalinova M, Schneider G, Kreyenberg H, Steinbach D, Weber G, Hollink IH, Zwaan CM, Biondi A, van der Velden VH, Reinhardt D, Cazzaniga G, Bader P, Trka J; European Study Group on WT1 Expression in Childhood AML. Willasch AM, et al. Among authors: gruhn b. Leukemia. 2009 Aug;23(8):1472-9. doi: 10.1038/leu.2009.51. Epub 2009 Mar 26. Leukemia. 2009. PMID: 19322206
The MLL recombinome of acute leukemias in 2017.
Meyer C, Burmeister T, Gröger D, Tsaur G, Fechina L, Renneville A, Sutton R, Venn NC, Emerenciano M, Pombo-de-Oliveira MS, Barbieri Blunck C, Almeida Lopes B, Zuna J, Trka J, Ballerini P, Lapillonne H, De Braekeleer M, Cazzaniga G, Corral Abascal L, van der Velden VHJ, Delabesse E, Park TS, Oh SH, Silva MLM, Lund-Aho T, Juvonen V, Moore AS, Heidenreich O, Vormoor J, Zerkalenkova E, Olshanskaya Y, Bueno C, Menendez P, Teigler-Schlegel A, Zur Stadt U, Lentes J, Göhring G, Kustanovich A, Aleinikova O, Schäfer BW, Kubetzko S, Madsen HO, Gruhn B, Duarte X, Gameiro P, Lippert E, Bidet A, Cayuela JM, Clappier E, Alonso CN, Zwaan CM, van den Heuvel-Eibrink MM, Izraeli S, Trakhtenbrot L, Archer P, Hancock J, Möricke A, Alten J, Schrappe M, Stanulla M, Strehl S, Attarbaschi A, Dworzak M, Haas OA, Panzer-Grümayer R, Sedék L, Szczepański T, Caye A, Suarez L, Cavé H, Marschalek R. Meyer C, et al. Among authors: gruhn b. Leukemia. 2018 Feb;32(2):273-284. doi: 10.1038/leu.2017.213. Epub 2017 Jul 13. Leukemia. 2018. PMID: 28701730 Free PMC article.
193 results