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High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.
Puglisi MA, Cenciarelli C, Tesori V, Cappellari M, Martini M, Di Francesco AM, Giorda E, Carsetti R, Ricci-Vitiani L, Gasbarrini A. Puglisi MA, et al. Among authors: di francesco am. J Pathol. 2015 Aug;236(4):479-90. doi: 10.1002/path.4545. Epub 2015 May 12. J Pathol. 2015. PMID: 25875314
Resistance to the atypical retinoid ST1926 in SK-N-AS cells selected the subline rAS-ST with enhanced sensitivity to ATRA mediated by not conventional mechanisms: DNA damage, G2 accumulation and late telomerase inhibition.
Di Francesco AM, Cusano G, Franzese O, Orienti I, Falconi M, Vesci L, Riccardi R. Di Francesco AM, et al. Toxicol In Vitro. 2015 Oct;29(7):1628-38. doi: 10.1016/j.tiv.2015.06.017. Epub 2015 Jun 19. Toxicol In Vitro. 2015. PMID: 26096597
The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects.
Cassinelli G, Zuco V, Petrangolini G, De Cesare M, Tortoreto M, Lanzi C, Cominetti D, Zaffaroni N, Orlandi A, Passeri D, Meco D, Di Francesco AM, Riccardi R, Bucci F, Pisano C, Zunino F. Cassinelli G, et al. Among authors: di francesco am. Biochem Pharmacol. 2012 Jul 15;84(2):163-71. doi: 10.1016/j.bcp.2012.04.005. Epub 2012 Apr 13. Biochem Pharmacol. 2012. PMID: 22525722
159 results