Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism.
Neaud V, Duplantier JG, Mazzocco C, Kisiel W, Rosenbaum J.
Neaud V, et al.
J Biol Chem. 2004 Feb 13;279(7):5200-6. doi: 10.1074/jbc.M306679200. Epub 2003 Nov 17.
J Biol Chem. 2004.
PMID: 14623891
Free article.
Here we show that thrombin itself up-regulates TFPI-2 mRNA and protein expression in human liver myofibroblasts, a cell type shown to express high levels of TFPI-2 (Neaud, V., Hisaka, T., Monvoisin, A., Bedin, C., Balabaud, C., Foster, D. C., Desmouliere, A., Kisiel …
Here we show that thrombin itself up-regulates TFPI-2 mRNA and protein expression in human liver myofibroblasts, a cell type shown to expres …