Glunz PW - Search Results

1

Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.

Glunz PW, Cheng X, Cheney DL, Weigelt CA, Wei A, Luettgen JM, Wong PC, Wexler RR, Priestley ES. Glunz PW, et al. Bioorg Med Chem Lett. 2015;25(10):2169-73. doi: 10.1016/j.bmcl.2015.03.062. Epub 2015 Mar 30. Bioorg Med Chem Lett. 2015. PMID: 25881820

2

Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors.

Glunz PW, Douty BD, Decicco CP. Glunz PW, et al. Bioorg Med Chem Lett. 2003 Mar 10;13(5):785-8. doi: 10.1016/s0960-894x(03)00022-2. Bioorg Med Chem Lett. 2003. PMID: 12617891

3

The synthesis and evaluation of a novel class of (E)-3-(1-cyclohexyl-1H-pyrazol-3-yl)-2-methylacrylic acid hepatitis C virus polymerase NS5B inhibitors.

Martin SW, Glunz P, Beno BR, Bergstrom C, Romine JL, Priestley ES, Newman M, Gao M, Roberts S, Rigat K, Fridell R, Qiu D, Knobloh G, Wang YK. Martin SW, et al. Bioorg Med Chem Lett. 2011 May 15;21(10):2869-72. doi: 10.1016/j.bmcl.2011.03.086. Epub 2011 Mar 30. Bioorg Med Chem Lett. 2011. PMID: 21507645

4

Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.

Zhang X, Glunz PW, Jiang W, Schmitt A, Newman M, Barbera FA, Bozarth JM, Rendina AR, Wei A, Wen X, Rossi KA, Luettgen JM, Wong PC, Knabb RM, Wexler RR, Scott Priestley E. Zhang X, et al. Among authors: glunz pw. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1604-7. doi: 10.1016/j.bmcl.2013.01.094. Epub 2013 Jan 30. Bioorg Med Chem Lett. 2013. PMID: 23416003

5

Nonbenzamidine acylsulfonamide tissue factor-factor VIIa inhibitors.

Glunz PW, Zhang X, Zou Y, Delucca I, Nirschl AH, Cheng X, Weigelt CA, Cheney DL, Wei A, Anumula R, Luettgen JM, Rendina AR, Harpel M, Luo G, Knabb R, Wong PC, Wexler RR, Priestley ES. Glunz PW, et al. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5244-8. doi: 10.1016/j.bmcl.2013.06.027. Epub 2013 Jun 21. Bioorg Med Chem Lett. 2013. PMID: 23845220

6

Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.

Zhang X, Jiang W, Jacutin-Porte S, Glunz PW, Zou Y, Cheng X, Nirschl AH, Wurtz NR, Luettgen JM, Rendina AR, Luo G, Harper TM, Wei A, Anumula R, Cheney DL, Knabb RM, Wong PC, Wexler RR, Priestley ES. Zhang X, et al. Among authors: glunz pw. ACS Med Chem Lett. 2013 Dec 26;5(2):188-92. doi: 10.1021/ml400453z. eCollection 2014 Feb 13. ACS Med Chem Lett. 2013. PMID: 24900796 Free PMC article.

7

Atropisomer Control in Macrocyclic Factor VIIa Inhibitors.

Glunz PW, Mueller L, Cheney DL, Ladziata V, Zou Y, Wurtz NR, Wei A, Wong PC, Wexler RR, Priestley ES. Glunz PW, et al. J Med Chem. 2016 Apr 28;59(8):4007-18. doi: 10.1021/acs.jmedchem.6b00244. Epub 2016 Apr 8. J Med Chem. 2016. PMID: 27015008

8

Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.

Zhang X, Glunz PW, Johnson JA, Jiang W, Jacutin-Porte S, Ladziata V, Zou Y, Phillips MS, Wurtz NR, Parkhurst B, Rendina AR, Harper TM, Cheney DL, Luettgen JM, Wong PC, Seiffert D, Wexler RR, Priestley ES. Zhang X, et al. Among authors: glunz pw. J Med Chem. 2016 Aug 11;59(15):7125-37. doi: 10.1021/acs.jmedchem.6b00469. Epub 2016 Aug 2. J Med Chem. 2016. PMID: 27455395

9

Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.

Ladziata VU, Glunz PW, Zou Y, Zhang X, Jiang W, Jacutin-Porte S, Cheney DL, Wei A, Luettgen JM, Harper TM, Wong PC, Seiffert D, Wexler RR, Priestley ES. Ladziata VU, et al. Among authors: glunz pw. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5051-5057. doi: 10.1016/j.bmcl.2016.08.088. Epub 2016 Aug 28. Bioorg Med Chem Lett. 2016. PMID: 27612545

10

Neutral macrocyclic factor VIIa inhibitors.

Wurtz NR, Parkhurst BL, DeLucca I, Glunz PW, Jiang W, Zhang X, Cheney DL, Bozarth JM, Rendina AR, Wei A, Harper T, Luettgen JM, Wu Y, Wong PC, Seiffert DA, Wexler RR, Priestley ES. Wurtz NR, et al. Among authors: glunz pw. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2650-2654. doi: 10.1016/j.bmcl.2017.04.008. Epub 2017 Apr 19. Bioorg Med Chem Lett. 2017. PMID: 28460818

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