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Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.
Ju KS, Gao J, Doroghazi JR, Wang KK, Thibodeaux CJ, Li S, Metzger E, Fudala J, Su J, Zhang JK, Lee J, Cioni JP, Evans BS, Hirota R, Labeda DP, van der Donk WA, Metcalf WW. Ju KS, et al. Among authors: doroghazi jr. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12175-80. doi: 10.1073/pnas.1500873112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324907 Free PMC article.
Nucleophilic 1,4-additions for natural product discovery.
Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA. Cox CL, et al. Among authors: doroghazi jr. ACS Chem Biol. 2014 Sep 19;9(9):2014-22. doi: 10.1021/cb500324n. Epub 2014 Jun 17. ACS Chem Biol. 2014. PMID: 24937678 Free PMC article.
Diversity and abundance of phosphonate biosynthetic genes in nature.
Yu X, Doroghazi JR, Janga SC, Zhang JK, Circello B, Griffin BM, Labeda DP, Metcalf WW. Yu X, et al. Among authors: doroghazi jr. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20759-64. doi: 10.1073/pnas.1315107110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297932 Free PMC article.
29 results