Eynard N - Search Results

1

Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone.

Grzegorzewicz AE, Eynard N, Quémard A, North EJ, Margolis A, Lindenberger JJ, Jones V, Korduláková J, Brennan PJ, Lee RE, Ronning DR, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: eynard n. ACS Infect Dis. 2015 Feb 13;1(2):91-97. doi: 10.1021/id500032q. ACS Infect Dis. 2015. PMID: 25897434 Free PMC article.

2

Rv3389C from Mycobacterium tuberculosis, a member of the (R)-specific hydratase/dehydratase family.

Sacco E, Legendre V, Laval F, Zerbib D, Montrozier H, Eynard N, Guilhot C, Daffé M, Quémard A. Sacco E, et al. Among authors: eynard n. Biochim Biophys Acta. 2007 Feb;1774(2):303-11. doi: 10.1016/j.bbapap.2006.11.016. Epub 2006 Dec 6. Biochim Biophys Acta. 2007. PMID: 17240207

3

Revisiting the assignment of Rv0241c to fatty acid synthase type II of Mycobacterium tuberculosis.

Sacco E, Slama N, Bäckbro K, Parish T, Laval F, Daffé M, Eynard N, Quémard A. Sacco E, et al. Among authors: eynard n. J Bacteriol. 2010 Aug;192(15):4037-44. doi: 10.1128/JB.00386-10. Epub 2010 May 28. J Bacteriol. 2010. PMID: 20511508 Free PMC article.

4

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system.

Slama N, Leiba J, Eynard N, Daffé M, Kremer L, Quémard A, Molle V. Slama N, et al. Among authors: eynard n. Biochem Biophys Res Commun. 2011 Sep 2;412(3):401-6. doi: 10.1016/j.bbrc.2011.07.051. Epub 2011 Jul 27. Biochem Biophys Res Commun. 2011. PMID: 21819969

5

The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.

Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffé M, Bäckbro K, Quémard A. Sacco E, et al. Among authors: eynard n. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14628-33. doi: 10.1073/pnas.0704132104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804795 Free PMC article.

6

Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis.

Lefebvre C, Frigui W, Slama N, Lauzeral-Vizcaino F, Constant P, Lemassu A, Parish T, Eynard N, Daffé M, Brosch R, Quémard A. Lefebvre C, et al. Among authors: eynard n. Sci Rep. 2020 Feb 7;10(1):2112. doi: 10.1038/s41598-020-58967-8. Sci Rep. 2020. PMID: 32034201 Free PMC article.

7

Bioinformatic Mining and Structure-Activity Profiling of Baeyer-Villiger Monooxygenases from Mycobacterium tuberculosis.

Tomas N, Leonelli D, Campoy M, Marthey S, Le NH, Rengel D, Martin V, Pál A, Korduláková J, Eynard N, Guillet V, Mourey L, Daffé M, Lemassu A, André G, Marrakchi H. Tomas N, et al. Among authors: eynard n. mSphere. 2022 Apr 27;7(2):e0048221. doi: 10.1128/msphere.00482-21. Epub 2022 Mar 17. mSphere. 2022. PMID: 35296143 Free PMC article.

8

The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.

Slama N, Jamet S, Frigui W, Pawlik A, Bottai D, Laval F, Constant P, Lemassu A, Cam K, Daffé M, Brosch R, Eynard N, Quémard A. Slama N, et al. Among authors: eynard n. Mol Microbiol. 2016 Feb;99(4):794-807. doi: 10.1111/mmi.13266. Epub 2015 Nov 27. Mol Microbiol. 2016. PMID: 26538472 Free article.

9

The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatis.

Jamet S, Slama N, Domingues J, Laval F, Texier P, Eynard N, Quémard A, Peixoto A, Lemassu A, Daffé M, Cam K. Jamet S, et al. Among authors: eynard n. PLoS One. 2015 Dec 23;10(12):e0145883. doi: 10.1371/journal.pone.0145883. eCollection 2015. PLoS One. 2015. PMID: 26701652 Free PMC article.

10

HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness.

Lefebvre C, Boulon R, Ducoux M, Gavalda S, Laval F, Jamet S, Eynard N, Lemassu A, Cam K, Bousquet MP, Bardou F, Burlet-Schiltz O, Daffé M, Quémard A. Lefebvre C, et al. Among authors: eynard n. Sci Rep. 2018 Apr 16;8(1):6034. doi: 10.1038/s41598-018-24380-5. Sci Rep. 2018. PMID: 29662082 Free PMC article.

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