Christian JL - Search Results

1

The prodomain of BMP4 is necessary and sufficient to generate stable BMP4/7 heterodimers with enhanced bioactivity in vivo.

Neugebauer JM, Kwon S, Kim HS, Donley N, Tilak A, Sopory S, Christian JL. Neugebauer JM, et al. Among authors: christian jl. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2307-16. doi: 10.1073/pnas.1501449112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902523 Free PMC article.

2

Regulation of BMP/Dpp signaling during embryonic development.

Nakayama T, Cui Y, Christian JL. Nakayama T, et al. Among authors: christian jl. Cell Mol Life Sci. 2000 Jun;57(6):943-56. doi: 10.1007/PL00000736. Cell Mol Life Sci. 2000. PMID: 10950309 Free PMC article. Review.

3

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor.

Cui Y, Hackenmiller R, Berg L, Jean F, Nakayama T, Thomas G, Christian JL. Cui Y, et al. Among authors: christian jl. Genes Dev. 2001 Nov 1;15(21):2797-802. doi: 10.1101/gad.940001. Genes Dev. 2001. PMID: 11691831 Free PMC article.

4

Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4.

Degnin C, Jean F, Thomas G, Christian JL. Degnin C, et al. Among authors: christian jl. Mol Biol Cell. 2004 Nov;15(11):5012-20. doi: 10.1091/mbc.e04-08-0673. Epub 2004 Sep 8. Mol Biol Cell. 2004. PMID: 15356272 Free PMC article.

5

Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity.

Goldman DC, Hackenmiller R, Nakayama T, Sopory S, Wong C, Kulessa H, Christian JL. Goldman DC, et al. Among authors: christian jl. Development. 2006 May;133(10):1933-42. doi: 10.1242/dev.02368. Epub 2006 Apr 19. Development. 2006. PMID: 16624858 Free article.

6

Regulation of bone morphogenetic protein-4 activity by sequence elements within the prodomain.

Sopory S, Nelsen SM, Degnin C, Wong C, Christian JL. Sopory S, et al. Among authors: christian jl. J Biol Chem. 2006 Nov 10;281(45):34021-31. doi: 10.1074/jbc.M605330200. Epub 2006 Sep 11. J Biol Chem. 2006. PMID: 16966322 Free article.

7

GATA-2 functions downstream of BMPs and CaM KIV in ectodermal cells during primitive hematopoiesis.

Dalgin G, Goldman DC, Donley N, Ahmed R, Eide CA, Christian JL. Dalgin G, et al. Among authors: christian jl. Dev Biol. 2007 Oct 15;310(2):454-69. doi: 10.1016/j.ydbio.2007.08.012. Epub 2007 Aug 16. Dev Biol. 2007. PMID: 17850784 Free PMC article.

8

Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.

Goldman DC, Donley N, Christian JL. Goldman DC, et al. Among authors: christian jl. Mech Dev. 2009 Mar-Apr;126(3-4):117-27. doi: 10.1016/j.mod.2008.11.008. Epub 2008 Dec 11. Mech Dev. 2009. PMID: 19116164 Free PMC article.

9

Site-specific cleavage of BMP4 by furin, PC6, and PC7.

Nelsen SM, Christian JL. Nelsen SM, et al. Among authors: christian jl. J Biol Chem. 2009 Oct 2;284(40):27157-66. doi: 10.1074/jbc.M109.028506. Epub 2009 Aug 3. J Biol Chem. 2009. PMID: 19651771 Free PMC article.

10

BMP4 regulates the hematopoietic stem cell niche.

Goldman DC, Bailey AS, Pfaffle DL, Al Masri A, Christian JL, Fleming WH. Goldman DC, et al. Among authors: christian jl. Blood. 2009 Nov 12;114(20):4393-401. doi: 10.1182/blood-2009-02-206433. Epub 2009 Sep 16. Blood. 2009. PMID: 19759357 Free PMC article.

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