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116 results

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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.
Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV. Xiang Y, et al. Among authors: milone mc. J Clin Invest. 2015 Jun;125(6):2293-306. doi: 10.1172/JCI75836. Epub 2015 Apr 27. J Clin Invest. 2015. PMID: 25915584 Free PMC article.
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR. Saha A, et al. Among authors: milone mc. J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13. J Clin Invest. 2016. PMID: 27294527 Free PMC article.
Itacitinib (INCB039110), a JAK1 Inhibitor, Reduces Cytokines Associated with Cytokine Release Syndrome Induced by CAR T-cell Therapy.
Huarte E, O'Connor RS, Peel MT, Nunez-Cruz S, Leferovich J, Juvekar A, Yang YO, Truong L, Huang T, Naim A, Milone MC, Smith PA. Huarte E, et al. Among authors: milone mc. Clin Cancer Res. 2020 Dec 1;26(23):6299-6309. doi: 10.1158/1078-0432.CCR-20-1739. Epub 2020 Sep 30. Clin Cancer Res. 2020. PMID: 32998963 Free PMC article.
CAR T cell immunotherapy for human cancer.
June CH, O'Connor RS, Kawalekar OU, Ghassemi S, Milone MC. June CH, et al. Among authors: milone mc. Science. 2018 Mar 23;359(6382):1361-1365. doi: 10.1126/science.aar6711. Science. 2018. PMID: 29567707 Review.
Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design.
Ghassemi S, Martinez-Becerra FJ, Master AM, Richman SA, Heo D, Leferovich J, Tu Y, García-Cañaveras JC, Ayari A, Lu Y, Wang A, Rabinowitz JD, Milone MC, June CH, O'Connor RS. Ghassemi S, et al. Among authors: milone mc. Mol Ther Methods Clin Dev. 2020 Jul 9;18:595-606. doi: 10.1016/j.omtm.2020.07.008. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32775494 Free PMC article.
Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene.
Sellmyer MA, Richman SA, Lohith K, Hou C, Weng CC, Mach RH, O'Connor RS, Milone MC, Farwell MD. Sellmyer MA, et al. Among authors: milone mc. Mol Ther. 2020 Jan 8;28(1):42-51. doi: 10.1016/j.ymthe.2019.10.007. Epub 2019 Oct 15. Mol Ther. 2020. PMID: 31668558 Free PMC article.
116 results