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The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase.
Vicuña L, Strochlic DE, Latremoliere A, Bali KK, Simonetti M, Husainie D, Prokosch S, Riva P, Griffin RS, Njoo C, Gehrig S, Mall MA, Arnold B, Devor M, Woolf CJ, Liberles SD, Costigan M, Kuner R. Vicuña L, et al. Among authors: costigan m. Nat Med. 2015 May;21(5):518-23. doi: 10.1038/nm.3852. Epub 2015 Apr 27. Nat Med. 2015. PMID: 25915831 Free PMC article.
GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, Ehnert C, Nejim J, Marian C, Scholz J, Wu T, Allchorne A, Diatchenko L, Binshtok AM, Goldman D, Adolph J, Sama S, Atlas SJ, Carlezon WA, Parsegian A, Lötsch J, Fillingim RB, Maixner W, Geisslinger G, Max MB, Woolf CJ. Tegeder I, et al. Among authors: costigan m. Nat Med. 2006 Nov;12(11):1269-77. doi: 10.1038/nm1490. Epub 2006 Oct 22. Nat Med. 2006. PMID: 17057711
GCH1, BH4 and pain.
Latremoliere A, Costigan M. Latremoliere A, et al. Among authors: costigan m. Curr Pharm Biotechnol. 2011 Oct;12(10):1728-41. doi: 10.2174/138920111798357393. Curr Pharm Biotechnol. 2011. PMID: 21466440 Free PMC article. Review.
Analgesia by inhibiting tetrahydrobiopterin synthesis.
Costigan M, Latremoliere A, Woolf CJ. Costigan M, et al. Curr Opin Pharmacol. 2012 Feb;12(1):92-9. doi: 10.1016/j.coph.2011.10.019. Epub 2011 Dec 15. Curr Opin Pharmacol. 2012. PMID: 22178186 Free PMC article. Review.
Combining Human and Rodent Genetics to Identify New Analgesics.
Latremoliere A, Costigan M. Latremoliere A, et al. Among authors: costigan m. Neurosci Bull. 2018 Feb;34(1):143-155. doi: 10.1007/s12264-017-0152-z. Epub 2017 Jul 1. Neurosci Bull. 2018. PMID: 28667479 Free PMC article. Review.
Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling.
Cobos EJ, Nickerson CA, Gao F, Chandran V, Bravo-Caparrós I, González-Cano R, Riva P, Andrews NA, Latremoliere A, Seehus CR, Perazzoli G, Nieto FR, Joller N, Painter MW, Ma CHE, Omura T, Chesler EJ, Geschwind DH, Coppola G, Rangachari M, Woolf CJ, Costigan M. Cobos EJ, et al. Among authors: costigan m. Cell Rep. 2018 Jan 30;22(5):1301-1312. doi: 10.1016/j.celrep.2018.01.006. Cell Rep. 2018. PMID: 29386116 Free PMC article.
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Latremoliere A, Latini A, Andrews N, Cronin SJ, Fujita M, Gorska K, Hovius R, Romero C, Chuaiphichai S, Painter M, Miracca G, Babaniyi O, Remor AP, Duong K, Riva P, Barrett LB, Ferreirós N, Naylor A, Penninger JM, Tegeder I, Zhong J, Blagg J, Channon KM, Johnsson K, Costigan M, Woolf CJ. Latremoliere A, et al. Among authors: costigan m. Neuron. 2015 Jun 17;86(6):1393-406. doi: 10.1016/j.neuron.2015.05.033. Neuron. 2015. PMID: 26087165 Free PMC article.
103 results