Kastner DL - Search Results

1

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, Alsaaty S, Park YH, Kastner DL, Chae JJ, Shelhamer JH. Sokolowska M, et al. Among authors: kastner dl. J Immunol. 2015 Jun 1;194(11):5472-5487. doi: 10.4049/jimmunol.1401343. Epub 2015 Apr 27. J Immunol. 2015. PMID: 25917098 Free PMC article.

2

The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments.

Mansfield E, Chae JJ, Komarow HD, Brotz TM, Frucht DM, Aksentijevich I, Kastner DL. Mansfield E, et al. Among authors: kastner dl. Blood. 2001 Aug 1;98(3):851-9. doi: 10.1182/blood.v98.3.851. Blood. 2001. PMID: 11468188 Free article.

3

De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases.

Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, Stein L, Russo R, Goldsmith D, Dent P, Rosenberg HF, Austin F, Remmers EF, Balow JE Jr, Rosenzweig S, Komarow H, Shoham NG, Wood G, Jones J, Mangra N, Carrero H, Adams BS, Moore TL, Schikler K, Hoffman H, Lovell DJ, Lipnick R, Barron K, O'Shea JJ, Kastner DL, Goldbach-Mansky R. Aksentijevich I, et al. Among authors: kastner dl. Arthritis Rheum. 2002 Dec;46(12):3340-8. doi: 10.1002/art.10688. Arthritis Rheum. 2002. PMID: 12483741 Free PMC article.

4

The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations.

Hull KM, Shoham N, Chae JJ, Aksentijevich I, Kastner DL. Hull KM, et al. Among authors: kastner dl. Curr Opin Rheumatol. 2003 Jan;15(1):61-9. doi: 10.1097/00002281-200301000-00011. Curr Opin Rheumatol. 2003. PMID: 12496512 Review.

5

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis.

Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Mol Cell. 2003 Mar;11(3):591-604. doi: 10.1016/s1097-2765(03)00056-x. Mol Cell. 2003. PMID: 12667444 Free article.

6

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9982-7. doi: 10.1073/pnas.0602081103. Epub 2006 Jun 19. Proc Natl Acad Sci U S A. 2006. PMID: 16785446 Free PMC article.

7

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment.

Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, Masters SL, Gumucio DL, Shoham NG, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Blood. 2008 Sep 1;112(5):1794-803. doi: 10.1182/blood-2008-01-134932. Epub 2008 Jun 24. Blood. 2008. PMID: 18577712 Free PMC article.

8

Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.

Chae JJ, Aksentijevich I, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Br J Haematol. 2009 Sep;146(5):467-78. doi: 10.1111/j.1365-2141.2009.07733.x. Epub 2009 May 14. Br J Haematol. 2009. PMID: 19466978 Free PMC article. Review.

9

Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

Booty MG, Chae JJ, Masters SL, Remmers EF, Barham B, Le JM, Barron KS, Holland SM, Kastner DL, Aksentijevich I. Booty MG, et al. Among authors: kastner dl. Arthritis Rheum. 2009 Jun;60(6):1851-61. doi: 10.1002/art.24569. Arthritis Rheum. 2009. PMID: 19479870 Free PMC article.

10

Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. Brydges SD, et al. Among authors: kastner dl. Immunity. 2009 Jun 19;30(6):875-87. doi: 10.1016/j.immuni.2009.05.005. Epub 2009 Jun 4. Immunity. 2009. PMID: 19501000 Free PMC article.

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