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Page 1
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, Gho JMIH, Tsiapras D, Vink A, Wu JC, Asselbergs FW, Li RA, Hulot JS, Kranias EG, Hajjar RJ. Karakikes I, et al. Among authors: kranias eg. Nat Commun. 2015 Apr 29;6:6955. doi: 10.1038/ncomms7955. Nat Commun. 2015. PMID: 25923014 Free PMC article.
Phospholamban gene dosage effects in the mammalian heart.
Luo W, Wolska BM, Grupp IL, Harrer JM, Haghighi K, Ferguson DG, Slack JP, Grupp G, Doetschman T, Solaro RJ, Kranias EG. Luo W, et al. Among authors: kranias eg. Circ Res. 1996 May;78(5):839-47. doi: 10.1161/01.res.78.5.839. Circ Res. 1996. PMID: 8620604
Phospholamban: a protein coming of age.
Kadambi VJ, Kranias EG. Kadambi VJ, et al. Among authors: kranias eg. Biochem Biophys Res Commun. 1997 Oct 9;239(1):1-5. doi: 10.1006/bbrc.1997.7340. Biochem Biophys Res Commun. 1997. PMID: 9345259 Review.
Type 1 phosphatase, a negative regulator of cardiac function.
Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, Kranias EG. Carr AN, et al. Among authors: kranias eg. Mol Cell Biol. 2002 Jun;22(12):4124-35. doi: 10.1128/MCB.22.12.4124-4135.2002. Mol Cell Biol. 2002. PMID: 12024026 Free PMC article.
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human.
Haghighi K, Kolokathis F, Pater L, Lynch RA, Asahi M, Gramolini AO, Fan GC, Tsiapras D, Hahn HS, Adamopoulos S, Liggett SB, Dorn GW 2nd, MacLennan DH, Kremastinos DT, Kranias EG. Haghighi K, et al. Among authors: kranias eg. J Clin Invest. 2003 Mar;111(6):869-76. doi: 10.1172/JCI17892. J Clin Invest. 2003. PMID: 12639993 Free PMC article.
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, Robbins J, Hewett TE, Bibb JA, Westfall MV, Kranias EG, Molkentin JD. Braz JC, et al. Among authors: kranias eg. Nat Med. 2004 Mar;10(3):248-54. doi: 10.1038/nm1000. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966518 Free article.
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1.
Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, McGraw DW, Heist EK, Guerrero JL, DePaoli-Roach AA, Hajjar RJ, Kranias EG. Pathak A, et al. Among authors: kranias eg. Circ Res. 2005 Apr 15;96(7):756-66. doi: 10.1161/01.RES.0000161256.85833.fa. Epub 2005 Mar 3. Circ Res. 2005. PMID: 15746443
328 results