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Lysine 63 ubiquitination is involved in the progression of tubular damage in diabetic nephropathy.
Pontrelli P, Conserva F, Papale M, Oranger A, Barozzino M, Vocino G, Rocchetti MT, Gigante M, Castellano G, Rossini M, Simone S, Laviola L, Giorgino F, Grandaliano G, Di Paolo S, Gesualdo L. Pontrelli P, et al. Among authors: oranger a. FASEB J. 2017 Jan;31(1):308-319. doi: 10.1096/fj.201600382RR. Epub 2016 Oct 24. FASEB J. 2017. PMID: 27881486
The purpose of our study was to evaluate how hyperglycemia (HG) influences Lys63 protein ubiquitination and its involvement in tubular damage and fibrosis in diabetic nephropathy (DN). Gene and protein expression of UBE2v1, a ubiquitin-conjugating E2-enzyme variant that me …
The purpose of our study was to evaluate how hyperglycemia (HG) influences Lys63 protein ubiquitination and its involvement in tubular damag …
Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy.
Pontrelli P, Oranger A, Barozzino M, Divella C, Conserva F, Fiore MG, Rossi R, Papale M, Castellano G, Simone S, Laviola L, Giorgino F, Piscitelli D, Gallone A, Gesualdo L. Pontrelli P, et al. Among authors: oranger a. J Mol Med (Berl). 2018 Jul;96(7):645-659. doi: 10.1007/s00109-018-1656-3. Epub 2018 May 27. J Mol Med (Berl). 2018. PMID: 29806072
66 results