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Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis.
Tichet M, Prod'Homme V, Fenouille N, Ambrosetti D, Mallavialle A, Cerezo M, Ohanna M, Audebert S, Rocchi S, Giacchero D, Boukari F, Allegra M, Chambard JC, Lacour JP, Michiels JF, Borg JP, Deckert M, Tartare-Deckert S. Tichet M, et al. Among authors: giacchero d. Nat Commun. 2015 Apr 30;6:6993. doi: 10.1038/ncomms7993. Nat Commun. 2015. PMID: 25925867 Free article.
Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.
Cerezo M, Tichet M, Abbe P, Ohanna M, Lehraiki A, Rouaud F, Allegra M, Giacchero D, Bahadoran P, Bertolotto C, Tartare-Deckert S, Ballotti R, Rocchi S. Cerezo M, et al. Among authors: giacchero d. Mol Cancer Ther. 2013 Aug;12(8):1605-15. doi: 10.1158/1535-7163.MCT-12-1226-T. Epub 2013 Jun 5. Mol Cancer Ther. 2013. PMID: 23741061
Metformin monotherapy in melanoma: a pilot, open-label, prospective, and multicentric study indicates no benefit.
Montaudié H, Cerezo M, Bahadoran P, Roger C, Passeron T, Machet L, Arnault JP, Verneuil L, Maubec E, Aubin F, Granel F, Giacchero D, Hofman V, Lacour JP, Maryline A, Ballotti R, Rocchi S. Montaudié H, et al. Among authors: giacchero d. Pigment Cell Melanoma Res. 2017 May;30(3):378-380. doi: 10.1111/pcmr.12576. Epub 2017 Apr 22. Pigment Cell Melanoma Res. 2017. PMID: 28122176 Clinical Trial. No abstract available.
A new KIT mutation (N505I) in acral melanoma confers constitutive signaling, favors tumorigenic properties, and is sensitive to imatinib.
Allegra M, Giacchero D, Segalen C, Dumaz N, Butori C, Hofman V, Hofman P, Lacour JP, Bertolotto C, Bahadoran P, Ballotti R. Allegra M, et al. Among authors: giacchero d. J Invest Dermatol. 2014 May;134(5):1473-1476. doi: 10.1038/jid.2013.525. Epub 2013 Dec 6. J Invest Dermatol. 2014. PMID: 24317392 Free article. No abstract available.
Dermoscopy of eccrine angiomatous hamartoma: The spitzoid pattern.
Kelati A, Chiaverini C, Giacchero D, Ilie M, Lacour JP, Bahadoran P. Kelati A, et al. Among authors: giacchero d. JAAD Case Rep. 2018 Sep 18;4(8):835-836. doi: 10.1016/j.jdcr.2018.06.026. eCollection 2018 Sep. JAAD Case Rep. 2018. PMID: 30238051 Free PMC article. No abstract available.
Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype.
Ohanna M, Cheli Y, Bonet C, Bonazzi VF, Allegra M, Giuliano S, Bille K, Bahadoran P, Giacchero D, Lacour JP, Boyle GM, Hayward NF, Bertolotto C, Ballotti R. Ohanna M, et al. Among authors: giacchero d. Oncotarget. 2013 Dec;4(12):2212-24. doi: 10.18632/oncotarget.1143. Oncotarget. 2013. PMID: 24344100 Free PMC article.
31 results