Betts C - Search Results

1

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. Godfrey C, et al. Among authors: betts c. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935000 Free PMC article.

2

Optimizing tissue-specific antisense oligonucleotide-peptide conjugates.

Betts CA, Hammond SM, Yin HF, Wood MJ. Betts CA, et al. Methods Mol Biol. 2012;867:415-35. doi: 10.1007/978-1-61779-767-5_27. Methods Mol Biol. 2012. PMID: 22454077

3

Cell penetrating peptide delivery of splice directing oligonucleotides as a treatment for Duchenne muscular dystrophy.

Betts CA, Wood MJ. Betts CA, et al. Curr Pharm Des. 2013;19(16):2948-62. doi: 10.2174/1381612811319160009. Curr Pharm Des. 2013. PMID: 23140454 Review.

4

Delivery of therapeutic oligonucleotides with cell penetrating peptides.

Boisguérin P, Deshayes S, Gait MJ, O'Donovan L, Godfrey C, Betts CA, Wood MJ, Lebleu B. Boisguérin P, et al. Among authors: betts ca. Adv Drug Deliv Rev. 2015 Jun 29;87:52-67. doi: 10.1016/j.addr.2015.02.008. Epub 2015 Mar 4. Adv Drug Deliv Rev. 2015. PMID: 25747758 Free PMC article. Review.

5

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice.

Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ. Betts CA, et al. Sci Rep. 2015 Mar 11;5:8986. doi: 10.1038/srep08986. Sci Rep. 2015. PMID: 25758104 Free PMC article.

6

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy.

Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJ. Betts CA, et al. Sci Rep. 2015 Jun 26;5:11632. doi: 10.1038/srep11632. Sci Rep. 2015. PMID: 26113184 Free PMC article.

7

Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics.

Coenen-Stass AM, McClorey G, Manzano R, Betts CA, Blain A, Saleh AF, Gait MJ, Lochmüller H, Wood MJ, Roberts TC. Coenen-Stass AM, et al. Among authors: betts ca. Sci Rep. 2015 Nov 23;5:17014. doi: 10.1038/srep17014. Sci Rep. 2015. PMID: 26594036 Free PMC article.

8

Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.

Coenen-Stass AM, Betts CA, Lee YF, Mäger I, Turunen MP, El Andaloussi S, Morgan JE, Wood MJ, Roberts TC. Coenen-Stass AM, et al. Among authors: betts ca. Hum Mol Genet. 2016 Sep 15;25(18):3960-3974. doi: 10.1093/hmg/ddw237. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466195 Free PMC article.

9

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW. Blain AM, et al. Among authors: betts ca. PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018. PLoS One. 2018. PMID: 29912990 Free PMC article.

10

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.

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