Godfrey C - Search Results

1

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. Godfrey C, et al. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935000 Free PMC article.

2

Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy.

Roberts TC, Blomberg KE, McClorey G, El Andaloussi S, Godfrey C, Betts C, Coursindel T, Gait MJ, Smith CI, Wood MJ. Roberts TC, et al. Among authors: godfrey c. Mol Ther Nucleic Acids. 2012 Aug 14;1(8):e39. doi: 10.1038/mtna.2012.26. Mol Ther Nucleic Acids. 2012. PMID: 23344181 Free PMC article.

3

Delivery of therapeutic oligonucleotides with cell penetrating peptides.

Boisguérin P, Deshayes S, Gait MJ, O'Donovan L, Godfrey C, Betts CA, Wood MJ, Lebleu B. Boisguérin P, et al. Among authors: godfrey c. Adv Drug Deliv Rev. 2015 Jun 29;87:52-67. doi: 10.1016/j.addr.2015.02.008. Epub 2015 Mar 4. Adv Drug Deliv Rev. 2015. PMID: 25747758 Free PMC article. Review.

4

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice.

Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ. Betts CA, et al. Among authors: godfrey c. Sci Rep. 2015 Mar 11;5:8986. doi: 10.1038/srep08986. Sci Rep. 2015. PMID: 25758104 Free PMC article.

5

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy.

Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJ. Betts CA, et al. Among authors: godfrey c. Sci Rep. 2015 Jun 26;5:11632. doi: 10.1038/srep11632. Sci Rep. 2015. PMID: 26113184 Free PMC article.

6

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration.

Roberts TC, Johansson HJ, McClorey G, Godfrey C, Blomberg KE, Coursindel T, Gait MJ, Smith CI, Lehtiö J, El Andaloussi S, Wood MJ. Roberts TC, et al. Among authors: godfrey c. Hum Mol Genet. 2015 Dec 1;24(23):6756-68. doi: 10.1093/hmg/ddv381. Epub 2015 Sep 18. Hum Mol Genet. 2015. PMID: 26385637 Free PMC article.

7

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Blain AM, Greally E, McClorey G, Manzano R, Betts CA, Godfrey C, O'Donovan L, Coursindel T, Gait MJ, Wood MJ, MacGowan GA, Straub VW. Blain AM, et al. Among authors: godfrey c. PLoS One. 2018 Jun 18;13(6):e0198897. doi: 10.1371/journal.pone.0198897. eCollection 2018. PLoS One. 2018. PMID: 29912990 Free PMC article.

8

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Among authors: godfrey c. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.

9

Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment.

Gait MJ, Arzumanov AA, McClorey G, Godfrey C, Betts C, Hammond S, Wood MJA. Gait MJ, et al. Among authors: godfrey c. Nucleic Acid Ther. 2019 Feb;29(1):1-12. doi: 10.1089/nat.2018.0747. Epub 2018 Oct 16. Nucleic Acid Ther. 2019. PMID: 30307373 Free PMC article. Review.

10

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment.

Betts C, Saleh AF, Arzumanov AA, Hammond SM, Godfrey C, Coursindel T, Gait MJ, Wood MJ. Betts C, et al. Among authors: godfrey c. Mol Ther Nucleic Acids. 2012 Aug 14;1(8):e38. doi: 10.1038/mtna.2012.30. Mol Ther Nucleic Acids. 2012. PMID: 23344180 Free PMC article.

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