Barker SE - Search Results

1

Long-term effect of gene therapy on Leber's congenital amaurosis.

Bainbridge JW, Mehat MS, Sundaram V, Robbie SJ, Barker SE, Ripamonti C, Georgiadis A, Mowat FM, Beattie SG, Gardner PJ, Feathers KL, Luong VA, Yzer S, Balaggan K, Viswanathan A, de Ravel TJ, Casteels I, Holder GE, Tyler N, Fitzke FW, Weleber RG, Nardini M, Moore AT, Thompson DA, Petersen-Jones SM, Michaelides M, van den Born LI, Stockman A, Smith AJ, Rubin G, Ali RR. Bainbridge JW, et al. Among authors: barker se. N Engl J Med. 2015 May 14;372(20):1887-97. doi: 10.1056/NEJMoa1414221. Epub 2015 May 4. N Engl J Med. 2015. PMID: 25938638 Free PMC article. Clinical Trial.

2

Gene therapy in the second eye of RPE65-deficient dogs improves retinal function.

Annear MJ, Bartoe JT, Barker SE, Smith AJ, Curran PG, Bainbridge JW, Ali RR, Petersen-Jones SM. Annear MJ, et al. Among authors: barker se. Gene Ther. 2011 Jan;18(1):53-61. doi: 10.1038/gt.2010.111. Epub 2010 Aug 12. Gene Ther. 2011. PMID: 20703309 Free PMC article.

3

Absence of ocular malignant transformation after sub-retinal delivery of rAAV2/2 or integrating lentiviral vectors in p53-deficient mice.

Balaggan KS, Duran Y, Georgiadis A, Thaung C, Barker SE, Buch PK, MacNeil A, Robbie S, Bainbridge JW, Smith AJ, Ali RR. Balaggan KS, et al. Among authors: barker se. Gene Ther. 2012 Feb;19(2):182-8. doi: 10.1038/gt.2011.194. Epub 2011 Nov 24. Gene Ther. 2012. PMID: 22113317

4

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.

Barker SE, Broderick CA, Robbie SJ, Duran Y, Natkunarajah M, Buch P, Balaggan KS, MacLaren RE, Bainbridge JW, Smith AJ, Ali RR. Barker SE, et al. J Gene Med. 2009 Jun;11(6):486-97. doi: 10.1002/jgm.1327. J Gene Med. 2009. PMID: 19340848 Free PMC article.

5

Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials.

Petersen-Jones SM, Annear MJ, Bartoe JT, Mowat FM, Barker SE, Smith AJ, Bainbridge JW, Ali RR. Petersen-Jones SM, et al. Among authors: barker se. Adv Exp Med Biol. 2012;723:177-82. doi: 10.1007/978-1-4614-0631-0_24. Adv Exp Med Biol. 2012. PMID: 22183331 Review. No abstract available.

6

Effective gene therapy with nonintegrating lentiviral vectors.

Yáñez-Muñoz RJ, Balaggan KS, MacNeil A, Howe SJ, Schmidt M, Smith AJ, Buch P, MacLaren RE, Anderson PN, Barker SE, Duran Y, Bartholomae C, von Kalle C, Heckenlively JR, Kinnon C, Ali RR, Thrasher AJ. Yáñez-Muñoz RJ, et al. Among authors: barker se. Nat Med. 2006 Mar;12(3):348-53. doi: 10.1038/nm1365. Epub 2006 Feb 19. Nat Med. 2006. PMID: 16491086

7

Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis.

Trittibach P, Barker SE, Broderick CA, Natkunarajah M, Duran Y, Robbie SJ, Bainbridge JW, Smith AJ, Sarra GM, Dick AD, Ali RR. Trittibach P, et al. Among authors: barker se. Gene Ther. 2008 Nov;15(22):1478-88. doi: 10.1038/gt.2008.109. Epub 2008 Jun 26. Gene Ther. 2008. PMID: 18580969 Free PMC article.

8

The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages.

Luhmann UF, Robbie S, Munro PM, Barker SE, Duran Y, Luong V, Fitzke FW, Bainbridge JW, Ali RR, MacLaren RE. Luhmann UF, et al. Among authors: barker se. Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5934-43. doi: 10.1167/iovs.09-3462. Epub 2009 Jul 2. Invest Ophthalmol Vis Sci. 2009. PMID: 19578022 Free PMC article.

9

Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation.

West EL, Pearson RA, Barker SE, Luhmann UF, Maclaren RE, Barber AC, Duran Y, Smith AJ, Sowden JC, Ali RR. West EL, et al. Among authors: barker se. Stem Cells. 2010 Nov;28(11):1997-2007. doi: 10.1002/stem.520. Stem Cells. 2010. PMID: 20857496 Free PMC article.

10

Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging.

Robbie SJ, Georgiadis A, Barker SE, Duran Y, Smith AJ, Ali RR, Luhmann UFO, Bainbridge JW. Robbie SJ, et al. Among authors: barker se. Neurobiol Aging. 2016 Apr;40:110-119. doi: 10.1016/j.neurobiolaging.2015.12.019. Epub 2016 Jan 4. Neurobiol Aging. 2016. PMID: 26973110

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