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A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.
Bečanović K, Nørremølle A, Neal SJ, Kay C, Collins JA, Arenillas D, Lilja T, Gaudenzi G, Manoharan S, Doty CN, Beck J, Lahiri N, Portales-Casamar E, Warby SC, Connolly C, De Souza RA; REGISTRY Investigators of the European Huntington's Disease Network; Tabrizi SJ, Hermanson O, Langbehn DR, Hayden MR, Wasserman WW, Leavitt BR. Bečanović K, et al. Among authors: wasserman ww. Nat Neurosci. 2015 Jun;18(6):807-16. doi: 10.1038/nn.4014. Epub 2015 May 4. Nat Neurosci. 2015. PMID: 25938884
Complete functional rescue of the ABCA1-/- mouse by human BAC transgenesis.
Coutinho JM, Singaraja RR, Kang M, Arenillas DJ, Bertram LN, Bissada N, Staels B, Fruchart JC, Fievet C, Joseph-George AM, Wasserman WW, Hayden MR. Coutinho JM, et al. Among authors: wasserman ww. J Lipid Res. 2005 Jun;46(6):1113-23. doi: 10.1194/jlr.M400506-JLR200. Epub 2005 Mar 16. J Lipid Res. 2005. PMID: 15772424 Free article.
In silico detection of sequence variations modifying transcriptional regulation.
Andersen MC, Engström PG, Lithwick S, Arenillas D, Eriksson P, Lenhard B, Wasserman WW, Odeberg J. Andersen MC, et al. Among authors: wasserman ww. PLoS Comput Biol. 2008 Jan;4(1):e5. doi: 10.1371/journal.pcbi.0040005. Epub 2007 Nov 27. PLoS Comput Biol. 2008. PMID: 18208319 Free PMC article.
Identification of a set of genes showing regionally enriched expression in the mouse brain.
D'Souza CA, Chopra V, Varhol R, Xie YY, Bohacec S, Zhao Y, Lee LL, Bilenky M, Portales-Casamar E, He A, Wasserman WW, Goldowitz D, Marra MA, Holt RA, Simpson EM, Jones SJ. D'Souza CA, et al. Among authors: wasserman ww. BMC Neurosci. 2008 Jul 14;9:66. doi: 10.1186/1471-2202-9-66. BMC Neurosci. 2008. PMID: 18625066 Free PMC article.
221 results