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Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension.
Marcotte D, Rushe M, M Arduini R, Lukacs C, Atkins K, Sun X, Little K, Cullivan M, Paramasivam M, Patterson TA, Hesson T, D McKee T, May-Dracka TL, Xin Z, Bertolotti-Ciarlet A, Bhisetti GR, Lyssikatos JP, Silvian LF. Marcotte D, et al. Protein Sci. 2017 Feb;26(2):152-162. doi: 10.1002/pro.3062. Epub 2016 Oct 21. Protein Sci. 2017. PMID: 27727493 Free PMC article.
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Graves B, Thompson T, Xia M, Janson C, Lukacs C, Deo D, Di Lello P, Fry D, Garvie C, Huang KS, Gao L, Tovar C, Lovey A, Wanner J, Vassilev LT. Graves B, et al. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11788-93. doi: 10.1073/pnas.1203789109. Epub 2012 Jun 28. Proc Natl Acad Sci U S A. 2012. PMID: 22745160 Free PMC article.
BglII and MunI: what a difference a base makes.
Lukacs CM, Aggarwal AK. Lukacs CM, et al. Curr Opin Struct Biol. 2001 Feb;11(1):14-8. doi: 10.1016/s0959-440x(00)00174-3. Curr Opin Struct Biol. 2001. PMID: 11179886 Review.
Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
Donnell AF, Michoud C, Rupert KC, Han X, Aguilar D, Frank KB, Fretland AJ, Gao L, Goggin B, Hogg JH, Hong K, Janson CA, Kester RF, Kong N, Le K, Li S, Liang W, Lombardo LJ, Lou Y, Lukacs CM, Mischke S, Moliterni JA, Polonskaia A, Schutt AD, Solis DS, Specian A, Taylor RT, Weisel M, Remiszewski SW. Donnell AF, et al. Among authors: lukacs cm. J Med Chem. 2013 Oct 24;56(20):7772-87. doi: 10.1021/jm400731m. Epub 2013 Oct 1. J Med Chem. 2013. PMID: 24083782
39 results