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Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel.
Arns S, Balgi AD, Shimizu Y, Pfeifer TA, Kumar N, Shidmoossavee FS, Sun S, Tai SS, Agafitei O, Jaquith JB, Bourque E, Niikura M, Roberge M. Arns S, et al. Eur J Med Chem. 2016 Sep 14;120:64-73. doi: 10.1016/j.ejmech.2016.05.008. Epub 2016 May 7. Eur J Med Chem. 2016. PMID: 27187859
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Frew J, Baradaran-Heravi A, Balgi AD, Wu X, Yan TD, Arns S, Shidmoossavee FS, Tan J, Jaquith JB, Jansen-West KR, Lynn FC, Gao FB, Petrucelli L, Feldman HH, Mackenzie IR, Roberge M, Nygaard HB. Frew J, et al. Among authors: arns s. Mol Neurodegener. 2020 Mar 16;15(1):21. doi: 10.1186/s13024-020-00369-5. Mol Neurodegener. 2020. PMID: 32178712 Free PMC article.
Corrigendum to "Assessing the oral bioavailability of difluorosialic acid prodrugs, potent viral neuraminidase inhibitors, using a snapshot PK screening assay" [Bioorg. Med. Chem. Lett. 25 (2015) 2505-2509].
Arns S, Tan J, Sun S, Galey A, Zisman N, Ross F, Udechukwu J, Dercho S, Gusti V, Paquette J, Wennekes T, Webb M, Bourque E, Withers SG, Liggins R. Arns S, et al. Bioorg Med Chem Lett. 2016 Jul 2:S0960-894X(16)30679-5. doi: 10.1016/j.bmcl.2016.06.068. Online ahead of print. Bioorg Med Chem Lett. 2016. PMID: 27381085 No abstract available.
28 results