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Classic reaction kinetics can explain complex patterns of antibiotic action.
Abel Zur Wiesch P, Abel S, Gkotzis S, Ocampo P, Engelstädter J, Hinkley T, Magnus C, Waldor MK, Udekwu K, Cohen T. Abel Zur Wiesch P, et al. Among authors: cohen t. Sci Transl Med. 2015 May 13;7(287):287ra73. doi: 10.1126/scitranslmed.aaa8760. Sci Transl Med. 2015. PMID: 25972005 Free PMC article.
The path of least resistance: aggressive or moderate treatment?
Kouyos RD, Metcalf CJ, Birger R, Klein EY, Abel zur Wiesch P, Ankomah P, Arinaminpathy N, Bogich TL, Bonhoeffer S, Brower C, Chi-Johnston G, Cohen T, Day T, Greenhouse B, Huijben S, Metlay J, Mideo N, Pollitt LC, Read AF, Smith DL, Standley C, Wale N, Grenfell B. Kouyos RD, et al. Among authors: cohen t. Proc Biol Sci. 2014 Nov 7;281(1794):20140566. doi: 10.1098/rspb.2014.0566. Proc Biol Sci. 2014. PMID: 25253451 Free PMC article.
Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations.
Hemez C, Clarelli F, Palmer AC, Bleis C, Abel S, Chindelevitch L, Cohen T, Abel Zur Wiesch P. Hemez C, et al. Among authors: cohen t. Comput Struct Biotechnol J. 2022 Aug 24;20:4688-4703. doi: 10.1016/j.csbj.2022.08.030. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36147681 Free PMC article.
1,396 results