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Classic reaction kinetics can explain complex patterns of antibiotic action.
Abel Zur Wiesch P, Abel S, Gkotzis S, Ocampo P, Engelstädter J, Hinkley T, Magnus C, Waldor MK, Udekwu K, Cohen T. Abel Zur Wiesch P, et al. Among authors: hinkley t. Sci Transl Med. 2015 May 13;7(287):287ra73. doi: 10.1126/scitranslmed.aaa8760. Sci Transl Med. 2015. PMID: 25972005 Free PMC article.
Assessing predicted HIV-1 replicative capacity in a clinical setting.
Kouyos RD, von Wyl V, Hinkley T, Petropoulos CJ, Haddad M, Whitcomb JM, Böni J, Yerly S, Cellerai C, Klimkait T, Günthard HF, Bonhoeffer S; Swiss HIV Cohort Study. Kouyos RD, et al. Among authors: hinkley t. PLoS Pathog. 2011 Nov;7(11):e1002321. doi: 10.1371/journal.ppat.1002321. Epub 2011 Nov 3. PLoS Pathog. 2011. PMID: 22072960 Free PMC article.
Exploring the complexity of the HIV-1 fitness landscape.
Kouyos RD, Leventhal GE, Hinkley T, Haddad M, Whitcomb JM, Petropoulos CJ, Bonhoeffer S. Kouyos RD, et al. Among authors: hinkley t. PLoS Genet. 2012;8(3):e1002551. doi: 10.1371/journal.pgen.1002551. Epub 2012 Mar 8. PLoS Genet. 2012. PMID: 22412384 Free PMC article.
Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds.
Yang WL, Kouyos RD, Böni J, Yerly S, Klimkait T, Aubert V, Scherrer AU, Shilaih M, Hinkley T, Petropoulos C, Bonhoeffer S, Günthard HF; Swiss HIV Cohort Study (SHCS). Yang WL, et al. Among authors: hinkley t. PLoS Pathog. 2015 Mar 23;11(3):e1004722. doi: 10.1371/journal.ppat.1004722. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25798934 Free PMC article. Clinical Trial.
118 results