Chan TD - Search Results

1

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.

Butt D, Chan TD, Bourne K, Hermes JR, Nguyen A, Statham A, O'Reilly LA, Strasser A, Price S, Schofield P, Christ D, Basten A, Ma CS, Tangye SG, Phan TG, Rao VK, Brink R. Butt D, et al. Among authors: chan td. Immunity. 2015 May 19;42(5):890-902. doi: 10.1016/j.immuni.2015.04.010. Epub 2015 May 12. Immunity. 2015. PMID: 25979420 Free article.

2

The SW(HEL) system for high-resolution analysis of in vivo antigen-specific T-dependent B cell responses.

Brink R, Paus D, Bourne K, Hermes JR, Gardam S, Phan TG, Chan TD. Brink R, et al. Among authors: chan td. Methods Mol Biol. 2015;1291:103-23. doi: 10.1007/978-1-4939-2498-1_9. Methods Mol Biol. 2015. PMID: 25836305

3

Affinity-based selection and the germinal center response.

Chan TD, Brink R. Chan TD, et al. Immunol Rev. 2012 May;247(1):11-23. doi: 10.1111/j.1600-065X.2012.01118.x. Immunol Rev. 2012. PMID: 22500828 Review.

4

Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.

Chan TD, Wood K, Hermes JR, Butt D, Jolly CJ, Basten A, Brink R. Chan TD, et al. Immunity. 2012 Nov 16;37(5):893-904. doi: 10.1016/j.immuni.2012.07.017. Epub 2012 Nov 8. Immunity. 2012. PMID: 23142780 Free article.

5

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.

Kräutler NJ, Suan D, Butt D, Bourne K, Hermes JR, Chan TD, Sundling C, Kaplan W, Schofield P, Jackson J, Basten A, Christ D, Brink R. Kräutler NJ, et al. Among authors: chan td. J Exp Med. 2017 May 1;214(5):1259-1267. doi: 10.1084/jem.20161533. Epub 2017 Mar 31. J Exp Med. 2017. PMID: 28363897 Free PMC article.

6

BAFFR controls early memory B cell responses but is dispensable for germinal center function.

Lau AWY, Turner VM, Bourne K, Hermes JR, Chan TD, Brink R. Lau AWY, et al. Among authors: chan td. J Exp Med. 2021 Feb 1;218(2):e20191167. doi: 10.1084/jem.20191167. J Exp Med. 2021. PMID: 33119033 Free PMC article.

7

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation.

Paus D, Phan TG, Chan TD, Gardam S, Basten A, Brink R. Paus D, et al. Among authors: chan td. J Exp Med. 2006 Apr 17;203(4):1081-91. doi: 10.1084/jem.20060087. Epub 2006 Apr 10. J Exp Med. 2006. PMID: 16606676 Free PMC article.

8

High affinity germinal center B cells are actively selected into the plasma cell compartment.

Phan TG, Paus D, Chan TD, Turner ML, Nutt SL, Basten A, Brink R. Phan TG, et al. Among authors: chan td. J Exp Med. 2006 Oct 30;203(11):2419-24. doi: 10.1084/jem.20061254. Epub 2006 Oct 9. J Exp Med. 2006. PMID: 17030950 Free PMC article.

9

Visualizing the effects of antigen affinity on T-dependent B-cell differentiation.

Brink R, Phan TG, Paus D, Chan TD. Brink R, et al. Among authors: chan td. Immunol Cell Biol. 2008 Jan;86(1):31-9. doi: 10.1038/sj.icb.7100143. Epub 2007 Nov 20. Immunol Cell Biol. 2008. PMID: 18026175 Review.

10

Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts.

Chan TD, Gatto D, Wood K, Camidge T, Basten A, Brink R. Chan TD, et al. J Immunol. 2009 Sep 1;183(5):3139-49. doi: 10.4049/jimmunol.0901690. Epub 2009 Aug 7. J Immunol. 2009. PMID: 19666691

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