Sheffield D - Search Results

1

Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin.

Jacquoilleot S, Sheffield D, Olayanju A, Sison-Young R, Kitteringham NR, Naisbitt DJ, Aleksic M. Jacquoilleot S, et al. Among authors: sheffield d. Toxicol Lett. 2015 Aug 19;237(1):11-20. doi: 10.1016/j.toxlet.2015.05.016. Epub 2015 May 26. Toxicol Lett. 2015. PMID: 26022718

2

Applying the skin sensitisation adverse outcome pathway (AOP) to quantitative risk assessment.

Maxwell G, MacKay C, Cubberley R, Davies M, Gellatly N, Glavin S, Gouin T, Jacquoilleot S, Moore C, Pendlington R, Saib O, Sheffield D, Stark R, Summerfield V. Maxwell G, et al. Among authors: sheffield d. Toxicol In Vitro. 2014 Feb;28(1):8-12. doi: 10.1016/j.tiv.2013.10.013. Epub 2013 Oct 31. Toxicol In Vitro. 2014. PMID: 24184331

3

Effect of Repeated Daily Dosing with 2,4-Dinitrochlorobenzene on Glutathione Biosynthesis and Nrf2 Activation in Reconstructed Human Epidermis.

Spriggs S, Sheffield D, Olayanju A, Kitteringham NR, Naisbitt DJ, Aleksic M. Spriggs S, et al. Among authors: sheffield d. Toxicol Sci. 2016 Nov;154(1):5-15. doi: 10.1093/toxsci/kfw140. Epub 2016 Aug 4. Toxicol Sci. 2016. PMID: 27492222

4

A study of inter-individual variability in the Phase II metabolism of xenobiotics in human skin.

Spriggs S, Cubberley R, Loadman P, Sheffield D, Wierzbicki A. Spriggs S, et al. Among authors: sheffield d. Toxicol Lett. 2018 Aug;292:63-72. doi: 10.1016/j.toxlet.2018.04.011. Epub 2018 Apr 27. Toxicol Lett. 2018. PMID: 29709425

5

PBK modelling of topical application and characterisation of the uncertainty of C_max estimate: A case study approach.

Li H, Reynolds J, Sorrell I, Sheffield D, Pendlington R, Cubberley R, Nicol B. Li H, et al. Among authors: sheffield d. Toxicol Appl Pharmacol. 2022 May 1;442:115992. doi: 10.1016/j.taap.2022.115992. Epub 2022 Mar 25. Toxicol Appl Pharmacol. 2022. PMID: 35346730 Free article.

6

Impact of a varied set of stimuli on a suite of immunological parameters within peripheral blood mononuclear cells: toward a non-animal approach for assessing immune modulation by materials intended for human use.

Cochrane S, Rajagopal R, Sheffield D, Stewart F, Hathaway L, Barnes NM, Qureshi O, Gordon J. Cochrane S, et al. Among authors: sheffield d. Front Toxicol. 2024 Apr 26;6:1335110. doi: 10.3389/ftox.2024.1335110. eCollection 2024. Front Toxicol. 2024. PMID: 38737195 Free PMC article.

7

Method validation and environmental monitoring of triethanolamine ester quaternary ammonium compounds.

Sparham C, Ledbetter M, Cubberley R, Gore D, Sheffield D, Teixeira A, Hodges G. Sparham C, et al. Among authors: sheffield d. Chemosphere. 2024 Jan;346:140529. doi: 10.1016/j.chemosphere.2023.140529. Epub 2023 Oct 30. Chemosphere. 2024. PMID: 37914048

8

Bioenergetics modelling to analyse and predict the joint effects of multiple stressors: Meta-analysis and model corroboration.

Goussen B, Rendal C, Sheffield D, Butler E, Price OR, Ashauer R. Goussen B, et al. Among authors: sheffield d. Sci Total Environ. 2020 Dec 20;749:141509. doi: 10.1016/j.scitotenv.2020.141509. Epub 2020 Aug 4. Sci Total Environ. 2020. PMID: 32827825 Free article.

9

Characteristics and purchasing behaviours of food-allergic consumers and those who buy food for them in Great Britain.

Cochrane SA, Gowland MH, Sheffield D, Crevel RW. Cochrane SA, et al. Among authors: sheffield d. Clin Transl Allergy. 2013 Sep 23;3(1):31. doi: 10.1186/2045-7022-3-31. Clin Transl Allergy. 2013. PMID: 24059866 Free PMC article.

10

Threshold dose for peanut: risk characterization based upon published results from challenges of peanut-allergic individuals.

Taylor SL, Crevel RW, Sheffield D, Kabourek J, Baumert J. Taylor SL, et al. Among authors: sheffield d. Food Chem Toxicol. 2009 Jun;47(6):1198-204. doi: 10.1016/j.fct.2009.02.011. Epub 2009 Feb 20. Food Chem Toxicol. 2009. PMID: 19232533 Review.

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