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The amyloidogenic light chain is a stressor that sensitizes plasma cells to proteasome inhibitor toxicity.
Oliva L, Orfanelli U, Resnati M, Raimondi A, Orsi A, Milan E, Palladini G, Milani P, Cerruti F, Cascio P, Casarini S, Rognoni P, Touvier T, Marcatti M, Ciceri F, Mangiacavalli S, Corso A, Merlini G, Cenci S. Oliva L, et al. Among authors: milan e. Blood. 2017 Apr 13;129(15):2132-2142. doi: 10.1182/blood-2016-08-730978. Epub 2017 Jan 27. Blood. 2017. PMID: 28130214 Free article.
Plasma cells require autophagy for sustainable immunoglobulin production.
Pengo N, Scolari M, Oliva L, Milan E, Mainoldi F, Raimondi A, Fagioli C, Merlini A, Mariani E, Pasqualetto E, Orfanelli U, Ponzoni M, Sitia R, Casola S, Cenci S. Pengo N, et al. Among authors: milan e. Nat Immunol. 2013 Mar;14(3):298-305. doi: 10.1038/ni.2524. Epub 2013 Jan 27. Nat Immunol. 2013. PMID: 23354484
Autophagy in Plasma Cell Ontogeny and Malignancy.
Milan E, Fabbri M, Cenci S. Milan E, et al. J Clin Immunol. 2016 May;36 Suppl 1:18-24. doi: 10.1007/s10875-016-0254-9. Epub 2016 Mar 16. J Clin Immunol. 2016. PMID: 26984755 Free PMC article. Review.
Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling.
Zhang XD, Baladandayuthapani V, Lin H, Mulligan G, Li B, Esseltine DW, Qi L, Xu J, Hunziker W, Barlogie B, Usmani SZ, Zhang Q, Crowley J, Hoering A, Shah JJ, Weber DM, Manasanch EE, Thomas SK, Li BZ, Wang HH, Zhang J, Kuiatse I, Tang JL, Wang H, He J, Yang J, Milan E, Cenci S, Ma WC, Wang ZQ, Davis RE, Yang L, Orlowski RZ. Zhang XD, et al. Among authors: milan e. Cancer Cell. 2016 May 9;29(5):639-652. doi: 10.1016/j.ccell.2016.03.026. Epub 2016 Apr 28. Cancer Cell. 2016. PMID: 27132469 Free PMC article.
150 results