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WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness.
Cuellar-Partida G, Springelkamp H, Lucas SE, Yazar S, Hewitt AW, Iglesias AI, Montgomery GW, Martin NG, Pennell CE, van Leeuwen EM, Verhoeven VJ, Hofman A, Uitterlinden AG, Ramdas WD, Wolfs RC, Vingerling JR, Brown MA, Mills RA, Craig JE, Klaver CC, van Duijn CM, Burdon KP, MacGregor S, Mackey DA. Cuellar-Partida G, et al. Among authors: hewitt aw. Hum Mol Genet. 2015 Sep 1;24(17):5060-8. doi: 10.1093/hmg/ddv211. Epub 2015 Jun 5. Hum Mol Genet. 2015. PMID: 26049155 Free article.
Central corneal thickness is highly heritable: the twin eye studies.
Toh T, Liew SH, MacKinnon JR, Hewitt AW, Poulsen JL, Spector TD, Gilbert CE, Craig JE, Hammond CJ, Mackey DA. Toh T, et al. Among authors: hewitt aw. Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3718-22. doi: 10.1167/iovs.04-1497. Invest Ophthalmol Vis Sci. 2005. PMID: 16186354 Free article.
439 results