Hu J - Search Results

1

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).

Hannan FM, Walls GV, Babinsky VN, Nesbit MA, Kallay E, Hough TA, Fraser WD, Cox RD, Hu J, Spiegel AM, Thakker RV. Hannan FM, et al. Among authors: hu j. Endocrinology. 2015 Sep;156(9):3114-21. doi: 10.1210/en.2015-1269. Epub 2015 Jun 8. Endocrinology. 2015. PMID: 26052899 Free PMC article.

2

Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators.

Hu J, Spiegel AM. Hu J, et al. J Cell Mol Med. 2007 Sep-Oct;11(5):908-22. doi: 10.1111/j.1582-4934.2007.00096.x. J Cell Mol Med. 2007. PMID: 17979873 Free PMC article. Review.

3

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.

Babinsky VN, Hannan FM, Gorvin CM, Howles SA, Nesbit MA, Rust N, Hanyaloglu AC, Hu J, Spiegel AM, Thakker RV. Babinsky VN, et al. Among authors: hu j. J Biol Chem. 2016 May 13;291(20):10876-85. doi: 10.1074/jbc.M115.696401. Epub 2016 Mar 18. J Biol Chem. 2016. PMID: 26994139 Free PMC article.

4

Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function.

Hu J, Spiegel AM. Hu J, et al. Trends Endocrinol Metab. 2003 Aug;14(6):282-8. doi: 10.1016/s1043-2760(03)00104-8. Trends Endocrinol Metab. 2003. PMID: 12890593 Review.

5

Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors.

Hauache OM, Hu J, Ray K, Xie R, Jacobson KA, Spiegel AM. Hauache OM, et al. Among authors: hu j. Endocrinology. 2000 Nov;141(11):4156-63. doi: 10.1210/endo.141.11.7753. Endocrinology. 2000. PMID: 11089548 Free PMC article.

6

Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor.

Hu J, Mora S, Weber G, Zamproni I, Proverbio MC, Spiegel AM. Hu J, et al. J Bone Miner Res. 2004 Apr;19(4):578-86. doi: 10.1359/JBMR.040106. Epub 2004 Jan 5. J Bone Miner Res. 2004. PMID: 15005845 Free article.

7

Autosomal dominant hypocalcemia caused by a novel mutation in the loop 2 region of the human calcium receptor extracellular domain.

Hu J, Mora S, Colussi G, Proverbio MC, Jones KA, Bolzoni L, De Ferrari ME, Civati G, Spiegel AM. Hu J, et al. J Bone Miner Res. 2002 Aug;17(8):1461-9. doi: 10.1359/jbmr.2002.17.8.1461. J Bone Miner Res. 2002. PMID: 12162500 Free article.

8

A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.

Hu J, McLarnon SJ, Mora S, Jiang J, Thomas C, Jacobson KA, Spiegel AM. Hu J, et al. J Biol Chem. 2005 Feb 11;280(6):5113-20. doi: 10.1074/jbc.M413403200. Epub 2004 Dec 9. J Biol Chem. 2005. PMID: 15591042 Free article.

9

A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.

Hu J, Jiang J, Costanzi S, Thomas C, Yang W, Feyen JHM, Jacobson KA, Spiegel AM. Hu J, et al. J Biol Chem. 2006 Jul 28;281(30):21558-21565. doi: 10.1074/jbc.M603682200. Epub 2006 May 30. J Biol Chem. 2006. PMID: 16735501 Free article.

10

Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors.

Hu J, Hauache O, Spiegel AM. Hu J, et al. J Biol Chem. 2000 May 26;275(21):16382-9. doi: 10.1074/jbc.M000277200. J Biol Chem. 2000. PMID: 10747888 Free article.

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