Núñez G - Search Results

1

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.

Gelfand BD, Wright CB, Kim Y, Yasuma T, Yasuma R, Li S, Fowler BJ, Bastos-Carvalho A, Kerur N, Uittenbogaard A, Han YS, Lou D, Kleinman ME, McDonald WH, Núñez G, Georgel P, Dunaief JL, Ambati J. Gelfand BD, et al. Among authors: nunez g. Cell Rep. 2015 Jun 23;11(11):1686-93. doi: 10.1016/j.celrep.2015.05.023. Epub 2015 Jun 11. Cell Rep. 2015. PMID: 26074074 Free PMC article.

2

Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.

Kanneganti TD, Body-Malapel M, Amer A, Park JH, Whitfield J, Franchi L, Taraporewala ZF, Miller D, Patton JT, Inohara N, Núñez G. Kanneganti TD, et al. Among authors: nunez g. J Biol Chem. 2006 Dec 1;281(48):36560-8. doi: 10.1074/jbc.M607594200. Epub 2006 Sep 28. J Biol Chem. 2006. PMID: 17008311 Free article.

3

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.

Franchi L, Núñez G. Franchi L, et al. Among authors: nunez g. Eur J Immunol. 2008 Aug;38(8):2085-9. doi: 10.1002/eji.200838549. Eur J Immunol. 2008. PMID: 18624356 Free PMC article.

4

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Nuñez G. Franchi L, et al. Among authors: nunez g. Nat Immunol. 2009 Mar;10(3):241-7. doi: 10.1038/ni.1703. Nat Immunol. 2009. PMID: 19221555 Free PMC article. Review.

5

Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation.

Franchi L, Eigenbrod T, Núñez G. Franchi L, et al. Among authors: nunez g. J Immunol. 2009 Jul 15;183(2):792-6. doi: 10.4049/jimmunol.0900173. Epub 2009 Jun 19. J Immunol. 2009. PMID: 19542372 Free PMC article.

6

Cholesterol-dependent cytolysins induce rapid release of mature IL-1beta from murine macrophages in a NLRP3 inflammasome and cathepsin B-dependent manner.

Chu J, Thomas LM, Watkins SC, Franchi L, Núñez G, Salter RD. Chu J, et al. Among authors: nunez g. J Leukoc Biol. 2009 Nov;86(5):1227-38. doi: 10.1189/jlb.0309164. Epub 2009 Aug 12. J Leukoc Biol. 2009. PMID: 19675207 Free PMC article.

7

A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome.

Muñoz-Planillo R, Franchi L, Miller LS, Núñez G. Muñoz-Planillo R, et al. Among authors: nunez g. J Immunol. 2009 Sep 15;183(6):3942-8. doi: 10.4049/jimmunol.0900729. Epub 2009 Aug 28. J Immunol. 2009. PMID: 19717510 Free PMC article.

8

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G. Harder J, et al. Among authors: nunez g. J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7. J Immunol. 2009. PMID: 19812205 Free PMC article.

9

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome.

Reimer T, Shaw MH, Franchi L, Coban C, Ishii KJ, Akira S, Horii T, Rodriguez A, Núñez G. Reimer T, et al. Among authors: nunez g. Eur J Immunol. 2010 Mar;40(3):764-9. doi: 10.1002/eji.200939996. Eur J Immunol. 2010. PMID: 19950187 Free PMC article.

10

Calcium-independent phospholipase A2 beta is dispensable in inflammasome activation and its inhibition by bromoenol lactone.

Franchi L, Chen G, Marina-Garcia N, Abe A, Qu Y, Bao S, Shayman JA, Turk J, Dubyak GR, Núñez G. Franchi L, et al. Among authors: nunez g. J Innate Immun. 2009;1(6):607-17. doi: 10.1159/000227263. J Innate Immun. 2009. PMID: 20160900 Free PMC article.

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