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Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.
Skurnik D, Davis MR Jr, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP. Skurnik D, et al. J Infect Dis. 2012 Jun;205(11):1709-18. doi: 10.1093/infdis/jis254. Epub 2012 Mar 23. J Infect Dis. 2012. PMID: 22448004 Free PMC article.
Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens.
Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier GB. Cywes-Bentley C, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2209-18. doi: 10.1073/pnas.1303573110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716675 Free PMC article.
Emergence of Antimicrobial-Resistant Escherichia coli of Animal Origin Spreading in Humans.
Skurnik D, Clermont O, Guillard T, Launay A, Danilchanka O, Pons S, Diancourt L, Lebreton F, Kadlec K, Roux D, Jiang D, Dion S, Aschard H, Denamur M, Cywes-Bentley C, Schwarz S, Tenaillon O, Andremont A, Picard B, Mekalanos J, Brisse S, Denamur E. Skurnik D, et al. Mol Biol Evol. 2016 Apr;33(4):898-914. doi: 10.1093/molbev/msv280. Epub 2015 Nov 26. Mol Biol Evol. 2016. PMID: 26613786 Free PMC article.
33 results