Dow LE - Search Results

1

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.

Dow LE, O'Rourke KP, Simon J, Tschaharganeh DF, van Es JH, Clevers H, Lowe SW. Dow LE, et al. Cell. 2015 Jun 18;161(7):1539-1552. doi: 10.1016/j.cell.2015.05.033. Cell. 2015. PMID: 26091037 Free PMC article.

2

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi.

Zuber J, McJunkin K, Fellmann C, Dow LE, Taylor MJ, Hannon GJ, Lowe SW. Zuber J, et al. Among authors: dow le. Nat Biotechnol. 2011 Jan;29(1):79-83. doi: 10.1038/nbt.1720. Epub 2010 Dec 5. Nat Biotechnol. 2011. PMID: 21131983 Free PMC article.

3

A rapid and scalable system for studying gene function in mice using conditional RNA interference.

Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. Premsrirut PK, et al. Among authors: dow le. Cell. 2011 Apr 1;145(1):145-58. doi: 10.1016/j.cell.2011.03.012. Cell. 2011. PMID: 21458673 Free PMC article.

4

Reversible suppression of an essential gene in adult mice using transgenic RNA interference.

McJunkin K, Mazurek A, Premsrirut PK, Zuber J, Dow LE, Simon J, Stillman B, Lowe SW. McJunkin K, et al. Among authors: dow le. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7113-8. doi: 10.1073/pnas.1104097108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482754 Free PMC article.

5

A pipeline for the generation of shRNA transgenic mice.

Dow LE, Premsrirut PK, Zuber J, Fellmann C, McJunkin K, Miething C, Park Y, Dickins RA, Hannon GJ, Lowe SW. Dow LE, et al. Nat Protoc. 2012 Feb 2;7(2):374-93. doi: 10.1038/nprot.2011.446. Nat Protoc. 2012. PMID: 22301776 Free PMC article.

6

Life in the fast lane: mammalian disease models in the genomics era.

Dow LE, Lowe SW. Dow LE, et al. Cell. 2012 Mar 16;148(6):1099-109. doi: 10.1016/j.cell.2012.02.023. Cell. 2012. PMID: 22424222 Free PMC article.

7

Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

Takiguchi M, Dow LE, Prier JE, Carmichael CL, Kile BT, Turner SJ, Lowe SW, Huang DC, Dickins RA. Takiguchi M, et al. Among authors: dow le. PLoS One. 2013;8(1):e54009. doi: 10.1371/journal.pone.0054009. Epub 2013 Jan 11. PLoS One. 2013. PMID: 23326559 Free PMC article.

8

Creating transgenic shRNA mice by recombinase-mediated cassette exchange.

Premsrirut PK, Dow LE, Park Y, Hannon GJ, Lowe SW. Premsrirut PK, et al. Among authors: dow le. Cold Spring Harb Protoc. 2013 Sep 1;2013(9):835-42. doi: 10.1101/pdb.prot077057. Cold Spring Harb Protoc. 2013. PMID: 24003198 Free PMC article.

9

Suppression of eukaryotic initiation factor 4E prevents chemotherapy-induced alopecia.

Nasr Z, Dow LE, Paquet M, Chu J, Ravindar K, Somaiah R, Deslongchamps P, Porco JA Jr, Lowe SW, Pelletier J. Nasr Z, et al. Among authors: dow le. BMC Pharmacol Toxicol. 2013 Nov 13;14:58. doi: 10.1186/2050-6511-14-58. BMC Pharmacol Toxicol. 2013. PMID: 24219888 Free PMC article.

10

A modular and flexible ESC-based mouse model of pancreatic cancer.

Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: dow le. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.

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