Long Y - Search Results

1

Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.

Tsai WB, Long Y, Park JR, Chang JT, Liu H, Rodriguez-Canales J, Savaraj N, Feun LG, Davies MA, Wistuba II, Kuo MT. Tsai WB, et al. Among authors: long y. Oncogene. 2016 Mar 31;35(13):1632-42. doi: 10.1038/onc.2015.237. Epub 2015 Jun 22. Oncogene. 2016. PMID: 26096933 Free PMC article.

2

Activation of Ras/PI3K/ERK pathway induces c-Myc stabilization to upregulate argininosuccinate synthetase, leading to arginine deiminase resistance in melanoma cells.

Tsai WB, Aiba I, Long Y, Lin HK, Feun L, Savaraj N, Kuo MT. Tsai WB, et al. Among authors: long y. Cancer Res. 2012 May 15;72(10):2622-33. doi: 10.1158/0008-5472.CAN-11-3605. Epub 2012 Mar 29. Cancer Res. 2012. PMID: 22461507 Free PMC article.

3

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation.

Long Y, Tsai WB, Chang JT, Estecio M, Wangpaichitr M, Savaraj N, Feun LG, Chen HH, Kuo MT. Long Y, et al. Oncotarget. 2016 Dec 13;7(50):82658-82670. doi: 10.18632/oncotarget.12308. Oncotarget. 2016. PMID: 27765932 Free PMC article.

4

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors.

Kuo MT, Long Y, Tsai WB, Li YY, Chen HHW, Feun LG, Savaraj N. Kuo MT, et al. Among authors: long y. Transl Oncol. 2020 Feb;13(2):355-364. doi: 10.1016/j.tranon.2019.12.003. Epub 2019 Dec 27. Transl Oncol. 2020. PMID: 31887630 Free PMC article.

5

Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy.

Long Y, Tsai WB, Wang D, Hawke DH, Savaraj N, Feun LG, Hung MC, Chen HH, Kuo MT. Long Y, et al. Cancer Lett. 2017 Mar 1;388:54-63. doi: 10.1016/j.canlet.2016.11.028. Epub 2016 Nov 30. Cancer Lett. 2017. PMID: 27913198

6

Arginine deiminase resistance in melanoma cells is associated with metabolic reprogramming, glucose dependence, and glutamine addiction.

Long Y, Tsai WB, Wangpaichitr M, Tsukamoto T, Savaraj N, Feun LG, Kuo MT. Long Y, et al. Mol Cancer Ther. 2013 Nov;12(11):2581-90. doi: 10.1158/1535-7163.MCT-13-0302. Epub 2013 Aug 26. Mol Cancer Ther. 2013. PMID: 23979920 Free PMC article.

7

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals.

Liang ZD, Long Y, Chen HH, Savaraj N, Kuo MT. Liang ZD, et al. Among authors: long y. J Biol Inorg Chem. 2014 Jan;19(1):17-27. doi: 10.1007/s00775-013-1051-z. Epub 2013 Oct 17. J Biol Inorg Chem. 2014. PMID: 24132751 Free PMC article.

8

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy.

Chen HH, Chen WC, Liang ZD, Tsai WB, Long Y, Aiba I, Fu S, Broaddus R, Liu J, Feun LG, Savaraj N, Kuo MT. Chen HH, et al. Among authors: long y. Expert Opin Ther Targets. 2015;19(10):1307-17. doi: 10.1517/14728222.2015.1043269. Epub 2015 May 25. Expert Opin Ther Targets. 2015. PMID: 26004625 Free PMC article. Review.

9

Gas6/Axl in arginine-starvation therapy.

Tsai WB, Long Y, Kuo MT. Tsai WB, et al. Among authors: long y. Oncoscience. 2015 Aug 25;2(8):659-60. doi: 10.18632/oncoscience.218. eCollection 2015. Oncoscience. 2015. PMID: 26425646 Free PMC article. No abstract available.

10

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression.

Tsai WB, Long Y, Chang JT, Savaraj N, Feun LG, Jung M, Chen HHW, Kuo MT. Tsai WB, et al. Among authors: long y. Sci Rep. 2017 Sep 7;7(1):10814. doi: 10.1038/s41598-017-11445-0. Sci Rep. 2017. PMID: 28883660 Free PMC article.

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