Barker HE - Search Results

1

The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence.

Barker HE, Paget JT, Khan AA, Harrington KJ. Barker HE, et al. Nat Rev Cancer. 2015 Jul;15(7):409-25. doi: 10.1038/nrc3958. Nat Rev Cancer. 2015. PMID: 26105538 Free PMC article. Review.

2

The rationale for targeting the LOX family in cancer.

Barker HE, Cox TR, Erler JT. Barker HE, et al. Nat Rev Cancer. 2012 Jul 19;12(8):540-52. doi: 10.1038/nrc3319. Nat Rev Cancer. 2012. PMID: 22810810 Review.

3

Trametinib radiosensitises RAS- and BRAF-mutated melanoma by perturbing cell cycle and inducing senescence.

Schick U, Kyula J, Barker H, Patel R, Zaidi S, Gregory C, Hafsi H, Roulstone V, Deutsch E, McLaughlin M, Harrington K. Schick U, et al. Radiother Oncol. 2015 Nov;117(2):364-75. doi: 10.1016/j.radonc.2015.06.026. Epub 2015 Jul 8. Radiother Oncol. 2015. PMID: 26163092

4

CHK1 Inhibition Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy.

Barker HE, Patel R, McLaughlin M, Schick U, Zaidi S, Nutting CM, Newbold KL, Bhide S, Harrington KJ. Barker HE, et al. Mol Cancer Ther. 2016 Sep;15(9):2042-54. doi: 10.1158/1535-7163.MCT-15-0998. Epub 2016 Jul 15. Mol Cancer Ther. 2016. PMID: 27422809

5

Radiosensitization by the ATR Inhibitor AZD6738 through Generation of Acentric Micronuclei.

Dillon MT, Barker HE, Pedersen M, Hafsi H, Bhide SA, Newbold KL, Nutting CM, McLaughlin M, Harrington KJ. Dillon MT, et al. Among authors: barker he. Mol Cancer Ther. 2017 Jan;16(1):25-34. doi: 10.1158/1535-7163.MCT-16-0239. Epub 2016 Nov 9. Mol Cancer Ther. 2017. PMID: 28062704 Free PMC article.

6

An orally bioavailable Chk1 inhibitor, CCT244747, sensitizes bladder and head and neck cancer cell lines to radiation.

Patel R, Barker HE, Kyula J, McLaughlin M, Dillon MT, Schick U, Hafsi H, Thompson A, Khoo V, Harrington K, Zaidi S. Patel R, et al. Among authors: barker he. Radiother Oncol. 2017 Mar;122(3):470-475. doi: 10.1016/j.radonc.2016.12.026. Epub 2017 Jan 25. Radiother Oncol. 2017. PMID: 28131548 Free PMC article.

7

HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.

McLaughlin M, Barker HE, Khan AA, Pedersen M, Dillon M, Mansfield DC, Patel R, Kyula JN, Bhide SA, Newbold KL, Nutting CM, Harrington KJ. McLaughlin M, et al. Among authors: barker he. BMC Cancer. 2017 Jan 31;17(1):86. doi: 10.1186/s12885-017-3084-0. BMC Cancer. 2017. PMID: 28143445 Free PMC article.

8

Combined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 Status.

Hafsi H, Dillon MT, Barker HE, Kyula JN, Schick U, Paget JT, Smith HG, Pedersen M, McLaughlin M, Harrington KJ. Hafsi H, et al. Among authors: barker he. Front Oncol. 2018 Jul 13;8:245. doi: 10.3389/fonc.2018.00245. eCollection 2018. Front Oncol. 2018. PMID: 30057890 Free PMC article.

9

Preclinical rare cancer research to inform clinical trial design.

Barker HE, Scott CL. Barker HE, et al. Nat Rev Cancer. 2019 Sep;19(9):481-482. doi: 10.1038/s41568-019-0172-2. Nat Rev Cancer. 2019. PMID: 31263218 No abstract available.

10

LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.

Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A, Erler JT. Barker HE, et al. Cancer Res. 2011 Mar 1;71(5):1561-72. doi: 10.1158/0008-5472.CAN-10-2868. Epub 2011 Jan 13. Cancer Res. 2011. PMID: 21233336 Free PMC article.

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