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Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model.
Luettich K, Xiang Y, Iskandar A, Sewer A, Martin F, Talikka M, Vanscheeuwijck P, Berges A, Veljkovic E, Gonzalez-Suarez I, Schlage W, Hoeng J, Peitsch M. Luettich K, et al. Among authors: sewer a. Interdiscip Toxicol. 2014 Jun;7(2):73-84. doi: 10.2478/intox-2014-0010. Epub 2014 Nov 15. Interdiscip Toxicol. 2014. PMID: 26109882 Free PMC article.
Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.
Mathis C, Poussin C, Weisensee D, Gebel S, Hengstermann A, Sewer A, Belcastro V, Xiang Y, Ansari S, Wagner S, Hoeng J, Peitsch MC. Mathis C, et al. Among authors: sewer a. Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L489-503. doi: 10.1152/ajplung.00181.2012. Epub 2013 Jan 25. Am J Physiol Lung Cell Mol Physiol. 2013. PMID: 23355383 Free PMC article.
Case study: the role of mechanistic network models in systems toxicology.
Hoeng J, Talikka M, Martin F, Sewer A, Yang X, Iskandar A, Schlage WK, Peitsch MC. Hoeng J, et al. Among authors: sewer a. Drug Discov Today. 2014 Feb;19(2):183-92. doi: 10.1016/j.drudis.2013.07.023. Epub 2013 Aug 9. Drug Discov Today. 2014. PMID: 23933191 Review.
49 results