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Page 1
mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.
Ito D, Nojima S, Nishide M, Okuno T, Takamatsu H, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Hosokawa T, Toyofuku T, Ohshima J, Kamimura D, Yamamoto M, Murakami M, Morii E, Rakugi H, Isaka Y, Kumanogoh A. Ito D, et al. Among authors: hosokawa t. J Immunol. 2015 Aug 1;195(3):934-43. doi: 10.4049/jimmunol.1403038. Epub 2015 Jun 26. J Immunol. 2015. PMID: 26116513 Free PMC article.
Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, Ito D, Morimoto K, Hosokawa T, Hayama Y, Mitsui Y, Sakurai N, Sarashina-Kida H, Nishide M, Maeda Y, Takamatsu H, Okuzaki D, Yamada M, Okada M, Kumanogoh A. Kimura T, et al. Among authors: hosokawa t. Nat Commun. 2016 Oct 12;7:13130. doi: 10.1038/ncomms13130. Nat Commun. 2016. PMID: 27731330 Free PMC article.
Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.
Hosokawa T, Kimura T, Nada S, Okuno T, Ito D, Kang S, Nojima S, Yamashita K, Nakatani T, Hayama Y, Kato Y, Kinehara Y, Nishide M, Mikami N, Koyama S, Takamatsu H, Okuzaki D, Ohkura N, Sakaguchi S, Okada M, Kumanogoh A. Hosokawa T, et al. J Immunol. 2017 Sep 15;199(6):2008-2019. doi: 10.4049/jimmunol.1700157. Epub 2017 Aug 2. J Immunol. 2017. PMID: 28768723
Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.
Hayama Y, Kimura T, Takeda Y, Nada S, Koyama S, Takamatsu H, Kang S, Ito D, Maeda Y, Nishide M, Nojima S, Sarashina-Kida H, Hosokawa T, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Koba T, Okada M, Kumanogoh A. Hayama Y, et al. Among authors: hosokawa t. J Immunol. 2018 Jun 1;200(11):3790-3800. doi: 10.4049/jimmunol.1701283. Epub 2018 Apr 23. J Immunol. 2018. PMID: 29686050
Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.
Yoshida Y, Ogata A, Kang S, Ebina K, Shi K, Nojima S, Kimura T, Ito D, Morimoto K, Nishide M, Hosokawa T, Hirano T, Shima Y, Narazaki M, Tsuboi H, Saeki Y, Tomita T, Tanaka T, Kumanogoh A. Yoshida Y, et al. Among authors: hosokawa t. Arthritis Rheumatol. 2015 Jun;67(6):1481-90. doi: 10.1002/art.39086. Arthritis Rheumatol. 2015. PMID: 25707877 Free PMC article.
LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.
Morimoto K, Baba Y, Shinohara H, Kang S, Nojima S, Kimura T, Ito D, Yoshida Y, Maeda Y, Sarashina-Kida H, Nishide M, Hosokawa T, Kato Y, Hayama Y, Kinehara Y, Okuno T, Takamatsu H, Hirano T, Shima Y, Narazaki M, Kurosaki T, Toyofuku T, Kumanogoh A. Morimoto K, et al. Among authors: hosokawa t. Sci Rep. 2016 May 11;6:25738. doi: 10.1038/srep25738. Sci Rep. 2016. PMID: 27166870 Free PMC article.
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.
Nishide M, Nojima S, Ito D, Takamatsu H, Koyama S, Kang S, Kimura T, Morimoto K, Hosokawa T, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Park JH, Hirano T, Shima Y, Narazaki M, Morii E, Kumanogoh A. Nishide M, et al. Among authors: hosokawa t. Ann Rheum Dis. 2017 Aug;76(8):1440-1448. doi: 10.1136/annrheumdis-2016-210706. Epub 2017 Apr 17. Ann Rheum Dis. 2017. PMID: 28416516 Free PMC article.
SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases.
Maeda Y, Tsuda T, Takeda Y, Koyama S, Hayama Y, Nojima S, Kimura T, Ito D, Takamatsu H, Kang S, Nishide M, Morimoto K, Hosokawa T, Kinehara Y, Kato Y, Nakatani T, Takeda K, Hayama M, Obata S, Akazawa H, Shikina T, Inohara H, Kumanogoh A. Maeda Y, et al. Among authors: hosokawa t. Allergol Int. 2019 Apr;68(2):274-276. doi: 10.1016/j.alit.2018.10.001. Epub 2018 Oct 19. Allergol Int. 2019. PMID: 30342889 Free article. No abstract available.
Erratum: Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, Ito D, Morimoto K, Hosokawa T, Hayama Y, Mitsui Y, Sakurai N, Sarashina-Kida H, Nishide M, Maeda Y, Takamatsu H, Okuzaki D, Yamada M, Okada M, Kumanogoh A. Kimura T, et al. Among authors: hosokawa t. Nat Commun. 2017 Feb 27;8:14711. doi: 10.1038/ncomms14711. Nat Commun. 2017. PMID: 28240287 Free PMC article. No abstract available.
897 results