Szymanski MR - Search Results

1

Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ.

Sohl CD, Szymanski MR, Mislak AC, Shumate CK, Amiralaei S, Schinazi RF, Anderson KS, Yin YW. Sohl CD, et al. Among authors: szymanski mr. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8596-601. doi: 10.1073/pnas.1421733112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124101 Free PMC article.

2

Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase.

Szymanski MR, Kuznetsov VB, Shumate C, Meng Q, Lee YS, Patel G, Patel S, Yin YW. Szymanski MR, et al. EMBO J. 2015 Jul 14;34(14):1959-70. doi: 10.15252/embj.201591520. Epub 2015 Jun 8. EMBO J. 2015. PMID: 26056153 Free PMC article.

3

The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity.

Li M, Mislak AC, Foli Y, Agbosu E, Bose V, Bhandari S, Szymanski MR, Shumate CK, Yin YW, Anderson KS, Paintsil E. Li M, et al. Among authors: szymanski mr. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5608-11. doi: 10.1128/AAC.00976-16. Print 2016 Sep. Antimicrob Agents Chemother. 2016. PMID: 27381400 Free PMC article.

4

A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.

Szymanski MR, Yu W, Gmyrek AM, White MA, Molineux IJ, Lee JC, Yin YW. Szymanski MR, et al. Nat Commun. 2017 May 3;8:14959. doi: 10.1038/ncomms14959. Nat Commun. 2017. PMID: 28466855 Free PMC article.

5

Transcription polymerase-catalyzed emergence of novel RNA replicons.

Jain N, Blauch LR, Szymanski MR, Das R, Tang SKY, Yin YW, Fire AZ. Jain N, et al. Among authors: szymanski mr. Science. 2020 Apr 10;368(6487):eaay0688. doi: 10.1126/science.aay0688. Epub 2020 Mar 26. Science. 2020. PMID: 32217750 Free PMC article.

6

Human EXOG Possesses Strong AP Hydrolysis Activity: Implication on Mitochondrial DNA Base Excision Repair.

Szymanski MR, Karlowicz A, Herrmann GK, Cen Y, Yin YW. Szymanski MR, et al. J Am Chem Soc. 2022 Dec 28;144(51):23543-23550. doi: 10.1021/jacs.2c10558. Epub 2022 Dec 14. J Am Chem Soc. 2022. PMID: 36516439 Free PMC article.

7

The Escherichia coli PriA helicase specifically recognizes gapped DNA substrates: effect of the two nucleotide-binding sites of the enzyme on the recognition process.

Szymanski MR, Jezewska MJ, Bujalowski W. Szymanski MR, et al. J Biol Chem. 2010 Mar 26;285(13):9683-9696. doi: 10.1074/jbc.M109.094789. Epub 2010 Jan 19. J Biol Chem. 2010. PMID: 20089865 Free PMC article.

8

Full-length Dengue virus RNA-dependent RNA polymerase-RNA/DNA complexes: stoichiometries, intrinsic affinities, cooperativities, base, and conformational specificities.

Szymanski MR, Jezewska MJ, Bujalowski PJ, Bussetta C, Ye M, Choi KH, Bujalowski W. Szymanski MR, et al. J Biol Chem. 2011 Sep 23;286(38):33095-108. doi: 10.1074/jbc.M111.255034. Epub 2011 Jul 2. J Biol Chem. 2011. PMID: 21725087 Free PMC article.

9

Interactions of the Escherichia coli primosomal PriB protein with the single-stranded DNA. Stoichiometries, intrinsic affinities, cooperativities, and base specificities.

Szymanski MR, Jezewska MJ, Bujalowski W. Szymanski MR, et al. J Mol Biol. 2010 Apr 23;398(1):8-25. doi: 10.1016/j.jmb.2010.02.009. Epub 2010 Feb 12. J Mol Biol. 2010. PMID: 20156448 Free PMC article.

10

Interactions of the DNA polymerase X from African Swine Fever Virus with the ssDNA. Properties of the total DNA-binding site and the strong DNA-binding subsite.

Jezewska MJ, Szymanski MR, Bujalowski W. Jezewska MJ, et al. Among authors: szymanski mr. Biophys Chem. 2011 Sep;158(1):26-37. doi: 10.1016/j.bpc.2011.04.012. Epub 2011 Apr 28. Biophys Chem. 2011. PMID: 21601347 Free PMC article.

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