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Two DNA-binding and nick recognition modules in human DNA ligase III.
Cotner-Gohara E, Kim IK, Tomkinson AE, Ellenberger T. Cotner-Gohara E, et al. Among authors: kim ik. J Biol Chem. 2008 Apr 18;283(16):10764-72. doi: 10.1074/jbc.M708175200. Epub 2008 Jan 30. J Biol Chem. 2008. PMID: 18238776 Free PMC article.
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.
Houl JH, Ye Z, Brosey CA, Balapiti-Modarage LPF, Namjoshi S, Bacolla A, Laverty D, Walker BL, Pourfarjam Y, Warden LS, Babu Chinnam N, Moiani D, Stegeman RA, Chen MK, Hung MC, Nagel ZD, Ellenberger T, Kim IK, Jones DE, Ahmed Z, Tainer JA. Houl JH, et al. Among authors: kim ik. Nat Commun. 2019 Dec 11;10(1):5654. doi: 10.1038/s41467-019-13508-4. Nat Commun. 2019. PMID: 31827085 Free PMC article.
14-3-3 proteins restrain the Exo1 nuclease to prevent overresection.
Chen X, Kim IK, Honaker Y, Paudyal SC, Koh WK, Sparks M, Li S, Piwnica-Worms H, Ellenberger T, You Z. Chen X, et al. Among authors: kim ik. J Biol Chem. 2015 May 8;290(19):12300-12. doi: 10.1074/jbc.M115.644005. Epub 2015 Apr 1. J Biol Chem. 2015. PMID: 25833945 Free PMC article.
An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2.
Moiani D, Link TM, Brosey CA, Katsonis P, Lichtarge O, Kim Y, Joachimiak A, Ma Z, Kim IK, Ahmed Z, Jones DE, Tsutakawa SE, Tainer JA. Moiani D, et al. Among authors: kim ik, kim y. Methods Enzymol. 2021;661:407-431. doi: 10.1016/bs.mie.2021.09.003. Epub 2021 Sep 27. Methods Enzymol. 2021. PMID: 34776222 Free PMC article.
959 results